Evidence map›Paper›PMID 27105053›Full record

ArticleAmerican journal of respiratory and critical care medicine2016

Influence of Lung Function and Sleep-disordered Breathing on All-Cause Mortality. A Community-based Study.

Nirupama Putcha, Ciprian Crainiceanu, Gina Norato, Jonathan Samet, Stuart F Quan, Daniel J Gottlieb, Susan Redline, Naresh M Punjabi

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
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  11. OSA and Chronic Respiratory Disease: Mechanisms and Epidemiology.International journal of environmental research and public health · 2022
    Review
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Obstructive sleep apnea and comorbidities: a dangerous liaison.Multidisciplinary respiratory medicine · 2019
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Nirupama Putcha1 Johns Hopkins University, Baltimore, Maryland.
Ciprian Crainiceanu1 Johns Hopkins University, Baltimore, Maryland.
Gina Norato1 Johns Hopkins University, Baltimore, Maryland.
Jonathan Samet2 University of Southern California, Los Angeles, California.
Stuart F Quan3 University of Arizona, Tucson, Arizona.
Daniel J Gottlieb4 Brigham and Women's Hospital and.
Susan Redline4 Brigham and Women's Hospital and.
Naresh M Punjabi1 Johns Hopkins University, Baltimore, Maryland.ORCID 0000-0003-1701-1550
Johns Hopkins University · USBrigham and Women's Hospital · USUniversity of Southern California · US

Funding

DATA COORDINATING CENTER FOR SLEEP HEART STUDYU01HL064360 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI DIENER-WEST, MARIE · 1999 to 2007
$4.4M
The Effects of Sleep Apnea on Metabolic FunctionR01HL075078 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI PUNJABI, NARESH M · 2003 to 2013
$3.3M
Treating Sleep Apnea in Type 2 Diabetes Mellitus: A Randomized Clinical TrialR01HL117167 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI PUNJABI, NARESH M · 2014 to 2017
$2.9M
THE SLEEP HEART HEALTH STUDY: READING CENTER APPLICATIONU01HL063463 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI REDLINE, SUSAN S. · 1999 to 2007
$2.8M
The Sleep Heart Health Study (SHHS)U01HL053938 · NHLBI · UNIVERSITY OF ARIZONA · PI QUAN, STUART F. · 1994 to 2007
$2.0M
SLEEP HEART HEALTH STUDYU01HL053931 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RAPOPORT, DAVID M. · 1994 to 2003
$1.9M
Statistical methods for biosignals with varying domainsR01HL123407 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CRAINICEANU, CIPRIAN M · 2014 to 2017
$1.6M
THE SLEEP HEART HEALTH STUDYU01HL053937 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI PUNJABI, NARESH · 1994 to 2007
$1.6M
SLEEP HEART HEALTH STUDYU01HL063429 · NHLBI · MISSOURI BREAKS RESEARCH, INC. · PI RESNICK, HELAINE E. · 1999 to 2007
$1.5M
SLEEP HEART HEALTH STUDYU01HL053916 · NHLBI · UNIVERSITY OF CALIFORNIA DAVIS · PI ROBBINS, JOHN A · 1994 to 2007
$1.5M
THE SLEEP HEART HEALTH STUDYU01HL053934 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SHAHAR, EYAL · 1994 to 2007
$1.4M
SLEEP HEART HEALTH STUDYU01HL053941 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI O'CONNOR, GEORGE T · 1994 to 2007
$1.4M
NHLBI NIH HHS K23 HL123594NHLBI NIH HHS R01 HL075078NHLBI NIH HHS R01 HL117167NHLBI NIH HHS R01 HL123407NHLBI NIH HHS U01 HL053916NHLBI NIH HHS U01 HL053931NHLBI NIH HHS U01 HL053934NHLBI NIH HHS U01 HL053937NHLBI NIH HHS U01 HL053938NHLBI NIH HHS U01 HL053941NHLBI NIH HHS U01 HL063429NHLBI NIH HHS U01 HL063463NHLBI NIH HHS U01 HL064360
6 · The paper itself

Abstract

rationaleWhether sleep-disordered breathing (SDB) severity and diminished lung function act synergistically to heighten the risk of adverse health outcomes remains a topic of significant debate.

objectivesThe current study sought to determine whether the association between lower lung function and mortality would be stronger in those with increasing severity of SDB in a community-based cohort of middle-aged and older adults.

methodsFull montage home sleep testing and spirometry data were analyzed on 6,173 participants of the Sleep Heart Health Study. Proportional hazards models were used to calculate risk for all-cause mortality, with FEV MEASUREMENTS AND MAIN

resultsAll-cause mortality rate was 26.9 per 1,000 person-years in those with SDB (AHI ≥5 events/h) and 18.2 per 1,000 person-years in those without (AHI <5 events/h). For every 200-ml decrease in FEV

conclusionsLung function was associated with risk for all-cause mortality. The incremental contribution of lung function to mortality diminishes with increasing severity of SDB.

Indexed as

AgedFemaleForced Expiratory VolumeHumansLungMaleMiddle AgedProportional Hazards ModelsRisk FactorsSeverity of Illness IndexSleep Apnea SyndromesSpirometryimpaired lung functionmortalitysleep apnea

Identifiers

PMID27105053
PMCPMC5067819
OpenAlexW2336741384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.