Evidence map›Paper›PMID 27104955›Full record

ArticleEpigenetics2018

Air pollution-induced placental epigenetic alterations in early life: a candidate miRNA approach.

Maria Tsamou, Karen Vrijens, Narjes Madhloum, Wouter Lefebvre, Charlotte Vanpoucke, Tim S Nawrot

Open access · hybridAbstract read
In one paragraph

Article in Epigenetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 3 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 106 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Does air pollution play a role in infertility?: a systematic review.Environmental health : a global access science source · 2017
    Pooled it
  4. Review
  5. Article
  6. Review
  7. Therapeutic nanoparticle safety in pregnancy: Bridging knowledge gaps with environmental insights and a translational roadmap.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Review
  8. Review
  9. Article
  10. Copy Number Variation in Asthma: An Integrative Review.Clinical reviews in allergy & immunology · 2025
    Review
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  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Maria Tsamoua Center for Environmental Sciences , Hasselt University , Hasselt , Belgium.
Karen Vrijensa Center for Environmental Sciences , Hasselt University , Hasselt , Belgium.
Narjes Madhlouma Center for Environmental Sciences , Hasselt University , Hasselt , Belgium.
Wouter Lefebvreb Flemish Institute for Technological Research (VITO) , Mol , Belgium.
Charlotte Vanpouckec Belgian Interregional Environment Agency (IRCELINE) , Brussels , Belgium.
Tim S Nawrota Center for Environmental Sciences , Hasselt University , Hasselt , Belgium.
Hasselt University · BEBelgian Development Agency · BEFlemish Institute for Technological Research · BEKU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Particulate matter (PM) exposure during in utero life may entail adverse health outcomes in later-life. Air pollution's adverse effects are known to alter gene expression profiles, which can be regulated by microRNAs (miRNAs). We investigate the potential influence of air pollution exposure in prenatal life on placental miRNA expression. Within the framework of the ENVIRONAGE birth cohort, we measured the expression of six candidate miRNAs in placental tissue from 210 mother-newborn pairs by qRT-PCR. Trimester-specific PM

Indexed as

Epigenesis, GeneticMaternal ExposureAdultAir PollutantsFemaleHumansInfant, NewbornMaleMicroRNAsParticulate MatterPlacentaPregnancyPTEN PhosphohydrolaseAir PollutantsMicroRNAsParticulate MatterPTEN Phosphohydrolaseair pollutionexpression analysismiRNAsparticulate matterplacenta

Identifiers

PMID27104955
PMCPMC5873362
OpenAlexW2336209849

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.