ArticlePsychiatry research2016
Ventrolateral prefrontal cortex repetitive transcranial magnetic stimulation in the treatment of depersonalization disorder: A consecutive case series.
Article in Psychiatry research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Co-occurrence of dissociation and anxiety and depressive disorders in adults: a scoping review.Frontiers in psychiatry · 2026Pooled it
- Dysfunctional large-scale brain networks in drug-naïve depersonalization-derealization disorder patients.BMC psychiatry · 2025Article
- Dissociative Symptoms and Interoceptive Integration.Current topics in behavioral neurosciences · 2025Review
- Predictors of posttraumatic stress disorder among displaced families in Lebanon: A cross-sectional study.PLOS global public health · 2025Article
- Unraveling the brain dynamics of Depersonalization-Derealization Disorder: a dynamic functional network connectivity analysis.BMC psychiatry · 2024Article
- Theta-burst direct electrical stimulation remodels human brain networks.Nature communications · 2024Article
- Survival, Attachment, and Healing: An Evolutionary Lens on Interventions for Trauma-Related Dissociation.Psychology research and behavior management · 2024Review
- Distinct resting-state effective connectivity of large-scale networks in first-episode and recurrent major depression disorder: evidence from the REST-meta-MDD consortium.Frontiers in neuroscience · 2023Article
- Depersonalization disorder as a systematic downregulation of interoceptive signals.Scientific reports · 2022Article
- Potential Targets for Noninvasive Brain Stimulation on Depersonalization-Derealization Disorder.Brain sciences · 2022Article
- Toward a Reasoned Classification of Diseases Using Physico-Chemical Based Phenotypes.Frontiers in physiology · 2018Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Case reports and an open trial have reported promising responses to repetitive transcranial magnetic stimulation (rTMS) to prefrontal and temporo-parietal sites in patients with depersonalization disorder (DPD). We recently showed that a single session of rTMS to the ventrolateral prefrontal cortex (VLPFC) was associated with a reduction in symptoms and increase in physiological arousal. Seven patients with medication-resistant DSM-IV DPD received up to 20 sessions of right-sided rTMS to the VLPFC for 10 weeks. Stimulation was guided using neuronavigation software based on participants' individual structural MRIs, and delivered at 110% of resting motor threshold. A session consisted of 1Hz repetitive TMS for 15min. The primary outcome measure was reduction in depersonalization symptoms on the Cambridge Depersonalization Scale (CDS). Secondary outcomes included scores on the Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI). 20 sessions of rTMS treatment to right VLPFC significantly reduced scores on the CDS by on average 44% (range 2-83.5%). Two patients could be classified as "full responders", four as "partial" and one a non-responder. Response usually occurred within the first 6 sessions. There were no significant adverse events. A randomized controlled clinical trial of VLPFC rTMS for DPD is warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.