ArticleEuropean journal of gastroenterology & hepatology2016
MRI characteristics for the differential diagnosis of benign and malignant small solitary hypovascular hepatic nodules.
Article in European journal of gastroenterology & hepatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 10 citations in OpenAlex.
- Article
- Malignant Tumors Misdiagnosed as Liver Hemangiomas.Frontiers in surgery · 2021Article
- Performance of Gd-EOB-DTPA-enhanced MRI for the diagnosis of LI-RADS 4 category hepatocellular carcinoma nodules with different diameters.Oncology letters · 2018Article
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4 authors at 2 institutions in 1 country.
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Abstract
purposeTo compare the MRI findings of benign and malignant solitary hypovascular hepatic nodules and identify the differentiating features. MATERIALS AND
methodsA total of 135 patients with solitary hypovascular hepatic lesions up to 3 cm (mass forming intrahepatic cholangiocarcinoma, n=29; metastases, n=26; inflammatory pseudotumors and solitary necrotic nodule, n=48; and hemangioma, n=32) were assessed. MRI findings were analyzed, and lesions were scored for peripheral and intratumoral appearance and enhancement patterns.
resultsUnivariate and multivariate analyses showed that the most common findings for benign lesions were subcapsular, sharp margin, homogeneous, marked high signal on T2WI, mild hyperintensity on T2WI, increasing intensity of peripheral globular enhancement, and persistent central septum-like linear enhancement on delayed phase (P<0.05). An area under the curve of 0.955 was obtained for differentiating malignant from benign nodules using the combined imaging features of ill-defined margins, heterogeneity, decreasing intensity of peripheral rim-like enhancement, and central increasing intensity of patchy enhancement. Interobserver agreement was good, ranging from 0.72 to 1.00.
conclusionMRI may be a useful noninvasive method for determining whether hypovascular hepatic nodules are malignant or benign.
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