Evidence map›Paper›PMID 27104610›Full record

ReviewThe journal of spinal cord medicine2017

Thoracic intradural extramedullary lesions causing progressive myelopathy as an initial manifestation of granulomatosis with polyangiitis: a case report and review of literature.

Yuki Taniguchi, Hirotaka Chikuda, Yasushi Oshima, Junichi Ohya, Yoshitaka Matsubayashi, Teppei Morikawa, Harumi Shirai, Oh Sasaki, Mihoko Shibuya, Keishi Fujio and 2 more

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The journal of spinal cord medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Yuki Taniguchia Department of Orthopedic Surgery , The University of Tokyo Hospital , Tokyo , Japan.
Hirotaka Chikudaa Department of Orthopedic Surgery , The University of Tokyo Hospital , Tokyo , Japan.
Yasushi Oshimaa Department of Orthopedic Surgery , The University of Tokyo Hospital , Tokyo , Japan.
Junichi Ohyaa Department of Orthopedic Surgery , The University of Tokyo Hospital , Tokyo , Japan.
Yoshitaka Matsubayashia Department of Orthopedic Surgery , The University of Tokyo Hospital , Tokyo , Japan.
Teppei Morikawab Department of Pathology , The University of Tokyo Hospital , Tokyo , Japan.
Harumi Shiraic Department of Allergy and Rheumatology , The University of Tokyo Hospital , Tokyo , Japan.
Oh Sasakic Department of Allergy and Rheumatology , The University of Tokyo Hospital , Tokyo , Japan.
Mihoko Shibuyac Department of Allergy and Rheumatology , The University of Tokyo Hospital , Tokyo , Japan.
Keishi Fujioc Department of Allergy and Rheumatology , The University of Tokyo Hospital , Tokyo , Japan.
Kazuhiko Yamamotoc Department of Allergy and Rheumatology , The University of Tokyo Hospital , Tokyo , Japan.
Sakae Tanakaa Department of Orthopedic Surgery , The University of Tokyo Hospital , Tokyo , Japan.
University of Tokyo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextTo our knowledge, only a few reports regarding the spinal involvement of granulomatosis with polyangiitis (GPA)-also termed as Wegener's granulomatosis-have been published. However, all these cases reportedly exhibited epidural tumor-like lesions or dural thickening.

findingsWe report the case of a 57-year-old woman with progressive myelopathy caused by multiple spinal lesions with GPA, which appeared to be protruding inwards, within the dura mater, on magnetic resonance imaging (MRI); these lesions were difficult to distinguish from intradural tumors. Moreover, these lesions exhibited low intensity on both T1- and T2-weighted MRI, and showed prominent enhancement on gadolinium-contrast imaging. Resection biopsy was effective for both diagnosis and the recovery of the neurological deficit.

conclusionBased on these findings, we suggest that GPA lesions can exhibit variable patterns in the spine. Nevertheless, clinicians should consider the possibility of GPA in such cases, particularly when multiple, inwardly protruding tumor-like lesions are detected within the dura mater on MRI.

Indexed as

Diagnosis, DifferentialDura MaterFemaleGranulomatosis with PolyangiitisHumansMiddle AgedSpinal Cord DiseasesSpinal Cord Neoplasms

Identifiers

PMID27104610
PMCPMC5376146
OpenAlexW2341148208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.