Evidence map›Paper›PMID 27103972›Full record

ArticleInfectious disease reports2016

Interleukin-6 Kinetics can be Useful for Early Treatment Monitoring of Severe Bacterial Sepsis and Septic Shock.

Thomas Klag, Giulio Cantara, Udo Sechtem, Anastasios Athanasiadis

Registry-linked trialAbstract readCase Reports
In one paragraph

Article in Infectious disease reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03643367 (Sevoflurane Sedation), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03643367 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Sevoflurane Sedation: A Potentially Promising Immunomodulation in Patients With Septic Shock

TypeinterventionalSponsorUniversity of ZurichRan2026 to 2027Enrolled153ConditionsShock, SepticArmsSevoflurane, Control Group
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The Importance of Haemogram Parameters in the Diagnosis and Prognosis of Septic Patients.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas KlagDivision of Gastroenterology.
Giulio CantaraDivision of Cardiology, Robert-Bosch-Hospital , Stuttgart, Germany.
Udo SechtemDivision of Cardiology, Robert-Bosch-Hospital , Stuttgart, Germany.
Anastasios AthanasiadisDivision of Cardiology, Robert-Bosch-Hospital , Stuttgart, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early appropriate anti-microbial therapy is necessary to improve outcomes of septic patients. We describe 20 case histories of patients with severe bacterial sepsis regarding kinetics of several biomarkers. We found that interleukin-6 is able to predict survival and might be able to evaluate appropriateness of anti-microbial therapy.

Indexed as

bacterial sepsisC reactive proteinInterleukin-6monitoringprocalcitonin

Identifiers

PMID27103972
PMCPMC4815941

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.