Evidence map›Paper›PMID 27103797›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2016

Does COPD risk vary by ethnicity? A retrospective cross-sectional study.

Alexander Gilkes, Mark Ashworth, Peter Schofield, Timothy H Harries, Stevo Durbaba, Charlotte Weston, Patrick White

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Multi-Ancestry Mendelian Randomization Reveals Lipid-Associated Genetic Risk Factors for COPD.International journal of chronic obstructive pulmonary disease · 2025
    Pooled it
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  17. COVID-19 and its Cardiac and Neurological Complications among Ontario Visible Minorities.The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2022
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  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alexander GilkesDepartment of Primary Care and Public Health Sciences, Division of Health and Social Care Research, Kings College London, London, UK.
Mark AshworthDepartment of Primary Care and Public Health Sciences, Division of Health and Social Care Research, Kings College London, London, UK.
Peter SchofieldDepartment of Primary Care and Public Health Sciences, Division of Health and Social Care Research, Kings College London, London, UK.
Timothy H HarriesDepartment of Primary Care and Public Health Sciences, Division of Health and Social Care Research, Kings College London, London, UK.
Stevo DurbabaDepartment of Primary Care and Public Health Sciences, Division of Health and Social Care Research, Kings College London, London, UK.
Charlotte WestonDepartment of Primary Care and Public Health Sciences, Division of Health and Social Care Research, Kings College London, London, UK.
Patrick WhiteDepartment of Primary Care and Public Health Sciences, Division of Health and Social Care Research, Kings College London, London, UK.
Department of Health and Social Care · GB

Funding

Department of Health NIHR-IPF-2014-08-06Medical Research Council MR/K021494/1
6 · The paper itself

Abstract

backgroundLower risk of COPD has been reported in black and Asian people, raising questions of poorer recognition or reduced susceptibility. We assessed prevalence and severity of COPD in ethnic groups, controlling for smoking.

methodA retrospective cross-sectional study using routinely collected primary care data in London. COPD prevalence, severity (% predicted forced expiratory volume in 1 second [FEV1]), smoking status, and treatment were compared between ethnic groups, adjusting for age, sex, smoking, deprivation, and practice clustering.

resultsAmong 358,614 patients in 47 general practices, 47.6% were white, 20% black, and 5% Asian. Prevalence of COPD was 1.01% overall, 1.55% in whites, 0.58% in blacks, and 0.78% in Asians. COPD was less likely in blacks (adjusted odds ratio [OR], 0.44; 95% confidence interval [CI] 0.39-0.51) and Asians (0.82; CI, 0.68-0.98) than whites. Black COPD patients were less likely to be current smokers (OR, 0.56; CI, 0.44-0.71) and more likely to be never-smokers (OR, 4.9; CI, 3.4-7.1). Treatment of patients with similar disease severity was similar irrespective of ethnic origin, except that long-acting muscarinic antagonists were prescribed less in black COPD patients (OR, 0.53; CI, 0.42-0.68). Black ethnicity was a predictor of poorer lung function (% predicted FEV1: B coefficient, -7.6; P<0.0001), an effect not seen when ethnic-specific predicted FEV1 values were used.

conclusionBlack people in London were half as likely as whites to have COPD after adjusting for lower smoking rates in blacks. It seems likely that the differences observed were due either to ethnic differences in the way cigarettes were smoked or to ethnic differences in susceptibility to COPD.

Indexed as

Asian PeopleBlack PeopleWhite PeopleAdultCross-Sectional StudiesFemaleHumansMalePrevalencePulmonary Disease, Chronic ObstructiveRetrospective StudiesRisk FactorsSeverity of Illness IndexCOPDethnicitysmoking

Identifiers

PMID27103797
PMCPMC4827905
OpenAlexW2318520127

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.