ReviewGastroenterology report2016
Heterotopic gastric mucosa in the anus and rectum: first case report of endoscopic submucosal dissection and systematic review.
Review in Gastroenterology report, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 37 citations in OpenAlex.
- A Rare Co-Occurrence of Gastric Heterotopia and Autonomic Nervous System Dysfunction: An Attempt to Explain If There Is a Need to Explore Possible Syndromic Link.Journal of medical cases · 2025Article
- Heterotopic gastric mucosa in the second part of the duodenum causing hemorrhage in a child: a case report and literature review.Frontiers in pediatrics · 2025Article
- Anal canal duplication with heterotopic gastric mucosa and anal stenosis: first case report and literature review.Frontiers in pediatrics · 2024Article
- An Unusual Case of Gastric Heterotopia Presenting as Rectal Prolapse.ACG case reports journal · 2024Article
- Life-threatening gastrointestinal bleeding caused by jejunal heterotopic gastric mucosa in an adult dog: a rare case report.BMC veterinary research · 2022Article
- Mass-Forming Gastric Heterotopia of the Rectum: A Series of 3 Cases from a Single Tertiary Health Center.The American journal of case reports · 2022Article
- Gastric heterotopia of colon found cancer workup in liver abscess: A case report.World journal of clinical cases · 2022Article
- Heterotopic Gastric Mucosa Causing Rectal Bleeding in a Young Child.JPGN reports · 2022Article
- How to trick artificial intelligence: rectal heterotopic gastric lateral spreading tumor.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2021Article
- Large heterotopic gastric mucosa and a concomitant diverticulum in the rectum: Clinical experience and endoscopic management.World journal of gastroenterology · 2018Review
- Endoscopic Mucosectomy in a Child Presenting with Gastric Heterotopia of the Rectum.GE Portuguese journal of gastroenterology · 2017Article
- Colorectal endoscopic submucosal dissection: predictors and neoplasm-related gradients of difficulty.Endoscopy international open · 2017Article
- Gastric heterotopia in rectum: A literature review and its diagnostic pitfall.SAGE open medical case reports · 2017Article
- Colonic tubular adenoma with incidental oxyntic gastric heterotopia.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHeterotopic gastric mucosa (HGM) is the most reported epithelial heterotopia, but it is very rare in the rectum and anus.
methodsThe first case of an asymptomatic adult male with a large nonpolypoid HGM in the low rectum underwent complete resection by endoscopic submucosal dissection (ESD) is reported. The systematic review was based on a comprehensive search of MEDLINE, EMBASE and Google Scholar. Studies on humans were identified with the term 'heterotopic gastric mucosa in the rectum and /or anus.'
resultsThe search identified 79 citations, and 72 cases were evaluated comprising the present report. Congenital malformations were observed in 17 (24%) patients; rectal duplication accounted for most of the cases. The HGM was located in the anus and perineal rectum in 25 cases (41%) and low, middle and proximal pelvic rectum in 20 (33%), five (8%) and 11 cases (18%), respectively. Morphology was nonpolypoid in 37 cases (51%), polypoid in 26 cases (36%) and ulcerated in nine cases (13%). Specific anorectal symptoms were reported by 50 (69%) patients of the whole study population, and by 33 (97%) of 34 patients ≤ 18 years. Complications were observed in 23 cases (32%). The HGM was excised in 50 cases (83%). Endoscopic resection was performed in 17 cases (34%); resection was piecemeal in five of 12 lesions ≥15 mm, required argon plasma coagulation in two cases and was associated with residual tissue in two (17%). Intestinal metaplasia and an adenoma with low-grade dysplasia were described in three adults (4%). DISCUSSION: This systematic review shows that the HGM in the rectum and anus may be associated with specific rectal symptoms and serious complications, mainly in the pediatric population, and a risk of malignancy in adults. Its complete excision should be recommended, and the ESD can overcome the technical limits of conventional endoscopic snare resection and avoid unnecessary surgery.
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