Evidence map›Paper›PMID 27103140›Full record

ArticleNeuroImage2016

STGP: Spatio-temporal Gaussian process models for longitudinal neuroimaging data.

Jung Won Hyun, Yimei Li, Chao Huang, Martin Styner, Weili Lin, Hongtu Zhu, Alzheimer's Disease Neuroimaging Initiative

Open access · bronzeAbstract read
In one paragraph

Article in NeuroImage, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Bayesian Spatial Blind Source Separation via the Thresholded Gaussian Process.Journal of the American Statistical Association · 2024
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  7. A Variational Approximation for Analyzing the Dynamics of Panel Data.Uncertainty in artificial intelligence : proceedings of the ... conference. Conference on Uncertainty in Artificial Intelligence · 2021
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  8. Review
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  10. Shape variation analyzer: a classifier for temporomandibular joint damaged by osteoarthritis.Proceedings of SPIE--the International Society for Optical Engineering · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jung Won HyunDepartment of Biostatistics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.
Yimei LiDepartment of Biostatistics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.
Chao HuangDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Martin StynerDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Weili LinDepartment of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Hongtu ZhuDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Alzheimer's Disease Neuroimaging Initiative
University of North Carolina at Chapel Hill · USSt. Jude Children's Research Hospital · US

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
North Carolina Translational & Clinical Sciences Institute (NC TraCS)UL1TR001111 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$43.9M
Statistical Analysis of Biomedical Imaging Data in Curved SpaceR01MH086633 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI IBRAHIM, JOSEPH G · 2010 to 2018
$2.9M
Biostatistics and Mental Health Neuroimaging and Genomics Training GrantT32MH106440 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GILMORE, JOHN HORACE, KOSOROK, MICHAEL R · 2015 to 2019
$970k
SCH: Proactive Health Monitoring Using Individualized Analysis of Tissue ElasticityR01EB020426 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIN, MING C. · 2014 to 2016
$653k
Longitudinal Analysis of Biomedical Imaging DataR21AG033387 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ZHU, HONGTU · 2009 to 2010
$334k
CIHRNCATS NIH HHS UL1 TR001111NCATS NIH HHS UL1 TR002489NIA NIH HHS R21 AG033387NIA NIH HHS U01 AG024904NIBIB NIH HHS R01 EB020426NIMH NIH HHS R01 MH086633NIMH NIH HHS T32 MH106440
6 · The paper itself

Abstract

Longitudinal neuroimaging data plays an important role in mapping the neural developmental profile of major neuropsychiatric and neurodegenerative disorders and normal brain. The development of such developmental maps is critical for the prevention, diagnosis, and treatment of many brain-related diseases. The aim of this paper is to develop a spatio-temporal Gaussian process (STGP) framework to accurately delineate the developmental trajectories of brain structure and function, while achieving better prediction by explicitly incorporating the spatial and temporal features of longitudinal neuroimaging data. Our STGP integrates a functional principal component model (FPCA) and a partition parametric space-time covariance model to capture the medium-to-large and small-to-medium spatio-temporal dependence structures, respectively. We develop a three-stage efficient estimation procedure as well as a predictive method based on a kriging technique. Two key novelties of STGP are that it can efficiently use a small number of parameters to capture complex non-stationary and non-separable spatio-temporal dependence structures and that it can accurately predict spatio-temporal changes. We illustrate STGP using simulated data sets and two real data analyses including longitudinal positron emission tomography data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) and longitudinal lateral ventricle surface data from a longitudinal study of early brain development.

Indexed as

Signal Processing, Computer-AssistedAgedAlzheimer DiseaseBrainComputer SimulationFemaleHumansLongitudinal StudiesMaleNeuroimagingNormal DistributionPositron-Emission TomographyPrincipal Component AnalysisFunctional principal component analysisKrigingNeuroimagingPredictionSpatio-temporal modeling

Identifiers

PMID27103140
PMCPMC4912881
OpenAlexW2340547861

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.