Evidence map›Paper›PMID 27102028›Full record

ArticleGlobal heart2016

Characteristics Associated With Antihypertensive Treatment and Blood Pressure Control: A Population-Based Follow-Up Study in Peru.

J Alfredo Zavala-Loayza, Catherine Pastorius Benziger, María Kathia Cárdenas, Rodrigo M Carrillo-Larco, Antonio Bernabé-Ortiz, Robert H Gilman, William Checkley, J Jaime Miranda, CRONICAS Cohort Study Group

Registry-linked trialAbstract read
In one paragraph

Article in Global heart, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05524987 (Addressing HyperteNsion and Diabetes Through Community-Engaged Systems in Puno, Peru), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05524987 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Addressing HyperteNsion and Diabetes Through Community-Engaged Systems in Puno, Peru (ANDES Study)

TypeinterventionalSponsorUniversidad Peruana Cayetano HerediaRan2023 to 2026Enrolled1,068ConditionsHypertension, DiabetesArmsANDES INTERVENTION
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

J Alfredo Zavala-LoayzaCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
Catherine Pastorius BenzigerUniversity of Washington, Seattle, WA, USA.
María Kathia CárdenasCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
Rodrigo M Carrillo-LarcoCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
Antonio Bernabé-OrtizCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
Robert H GilmanCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru; Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA; Área de Investigación y Desarrollo, Asociación Benéfica PRISMA, Lima, Peru.
William CheckleyCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru; Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA; Division of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, Maryland, MD, USA.
J Jaime MirandaCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru; Facultad de Medicina "Alberto Hurtado", Universidad Peruana Cayetano Heredia, Lima, Peru. Electronic address: jaime.miranda@upch.pe.
CRONICAS Cohort Study Group

Funding

Implementation of foot thermometry and SMS to prevent diabetic foot ulcerR21TW009982 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI MIRANDA, J JAIME · 2014 to 2015
$329k
FIC NIH HHS R21 TW009982Medical Research Council MR/K007467/1NHLBI NIH HHS HHSN268200900033CNHLBI NIH HHS HHSN 268200900033C-1-0-1NHLBI NIH HHS HHSN268200900034C
6 · The paper itself

Abstract

backgroundOver one-quarter of the world's adult population has hypertension, yet achieving adequate treatment or control targets remains a challenge.

objectiveThis study sought to identify, longitudinally, characteristics associated with antihypertensive treatment and blood pressure (BP) control among individuals with hypertension.

methodsData from individuals enrolled in the population-based CRONICAS Cohort Study (adults ≥35 years, living in 4 different rural/urban and coastal/high-altitude Peruvian settings) with hypertension at baseline were used. Antihypertensive treatment and BP control were assessed at baseline and at 15 months. Multinomial logistic regressions were used to estimate relative risk ratios (RRR) and 95% confidence intervals (95% CI) of factors associated with antihypertensive treatment and BP control at follow-up.

resultsAt baseline, among 717 individuals with hypertension (53% women, mean age 61.5 ± 12.4 years), 28% were unaware of their hypertension status, 30% were aware but untreated, 16% were treated but uncontrolled, and 26% were treated and controlled. At follow-up, 89% of unaware and 82% of untreated individuals persisted untreated, and only 58% of controlled individuals remained controlled. Positive predictors of receiving treatment and being controlled at follow-up included age (RRR: 0.81; 95% CI: 0.73 to 0.91 for every 5 years) and family history of a chronic disease (RRR: 0.53; 95% CI: 0.31 to 0.92 vs. no history); whereas Puno rural site (RRR: 16.51; 95% CI: 1.90 to 143.56 vs. Lima) and male sex (RRR: 2.59; 95% CI: 1.54 to 4.36) were risk factors. Systolic BP at baseline (RRR: 1.27; 95% CI: 1.16 to 1.39 for every 5 mm Hg) and male sex (RRR: 1.75, 95% CI: 1.02 to 2.98) were risk factors for being treated but uncontrolled at follow-up.

conclusionsLarge gaps in treatment of hypertension were observed. Targeting specific populations such as men, younger individuals, or those without family history of disease may increase coverage of antihypertensive treatment. Also, targeting male individuals or those with higher systolic BP could yield better rates of BP control in the short term.

Indexed as

Blood PressureHealth Knowledge, Attitudes, PracticeAdultAgedAge FactorsAntihypertensive AgentsFemaleFollow-Up StudiesHumansHypertensionLogistic ModelsLongitudinal StudiesMaleMiddle AgedPeruRisk FactorsAntihypertensive Agents

Identifiers

PMID27102028
PMCPMC4843839

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.