ArticleMolecular and cellular biochemistry2016
Evaluation of the effect of n-3 PUFA-rich dietary fish oils on lipid profile and membrane fluidity in alloxan-induced diabetic mice (Mus musculus).
Article in Molecular and cellular biochemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Effects of 12-week supplementation of marine Omega-3 PUFA-based formulation Omega3Q10 in older adults with prehypertension and/or elevated blood cholesterol.Lipids in health and disease · 2017Trial
- Effect of n-3 Polyunsaturated Fatty Acid Supplementation on Metabolic and Inflammatory Biomarkers in Type 2 Diabetes Mellitus Patients.Nutrients · 2017Trial
- Mitochondrial Damage and Autophagy Dysregulation in Alzheimer's Disease: Mechanisms and Therapeutic Opportunities.Neurochemical research · 2025Review
- The Cardioprotective Effects of Polyunsaturated Fatty Acids Depends on the Balance Between Their Anti- and Pro-Oxidative Properties.Nutrients · 2024Review
- A novel in vitro approach to test the effectiveness of fish oil in ameliorating type 1 diabetes.Molecular and cellular biochemistry · 2022Article
- Association of Maternal Erythrocyte PUFA during Pregnancy with Offspring Allergy in the Chinese Population.Nutrients · 2022Article
- Dietary α-Linolenic Acid Counters Cardioprotective Dysfunction in Diabetic Mice: Unconventional PUFA Protection.Nutrients · 2020Article
- Article
- Can Yellow Stripe Scad Compete with Salmon on Its Role in Platelet Phospholipid Membrane and Its Cardiovascular Benefits?Journal of obesity · 2019Review
- Dietary canolol protects the heart against the deleterious effects induced by the association of rapeseed oil, vitamin E and coenzyme Q10 in the context of a high-fat diet.Nutrition & metabolism · 2018Article
- Myocyte membrane and microdomain modifications in diabetes: determinants of ischemic tolerance and cardioprotection.Cardiovascular diabetology · 2017Review
- Hypolipidemic effect of β-caryophyllene to treat hyperlipidemic rats.Naunyn-Schmiedeberg's archives of pharmacology · 2017Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Marine fishes are important to health due to their high content of polyunsaturated fatty acids particularly those of the omega-3 family. These fatty acids play an important role in various physiological processes and as a consequence they may modulate and even prevent some human diseases. The aim of the present study was to investigate and compare the effect of fish oils of different origins (Sardinella longiceps, Rastrelliger kanagurta and Clarias batrachus) on lipid metabolism and membrane fluidity in diabetes. Alloxan was injected in repetitive doses for 1 month (100 mg/kg body weight every 5th day) to induce diabetes in Swiss albino mice. 10 % S. longiceps, R. kanagurta or C. batrachus fish oil was freshly blended with pellet feed which was provided to diabetic mice for 1 month. The serum lipid profile (serum total cholesterol, triglyceride, HDL, VLDL and LDL) along with liver, kidney and heart tissue lipid profile (i.e. triglyceride, total cholesterol, glycolipid and phospholipid) was analysed. Besides, the enzymatic activity of HMG-CoA reductase, HMG-CoA synthase and glucose-6-phosphate-dehydrogenase along with the membrane fluidity of these tissues was evaluated. Altered tissue lipid composition, enzyme activities and membrane fluidity due to diabetes were returned towards normal with the supplementation of 10 % fish oils. Fish oil from S. longiceps brought maximum changes in level of neutral lipid composition in heart, and increased the concentration of phospholipid and decreased the activity of HMG-CoA reductase in comparison with the fish oil from R. kanagurta and C. batrachus.
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