ArticleClinical and experimental nephrology2017
Efficacy of low-density lipoprotein apheresis combined with corticosteroids for cholesterol crystal embolism.
Article in Clinical and experimental nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 15 citations in OpenAlex.
- Blue Toe Syndrome Responding to Direct Hemoadsorption Therapy with the RheocarnaInternal medicine (Tokyo, Japan) · 2025Article
- An Autopsy Case of Acute Pancreatitis Caused by Cholesterol Crystal Embolization.Internal medicine (Tokyo, Japan) · 2021Article
- Proportion and risk factors of cholesterol crystal embolization after cardiovascular procedures: a retrospective national database study.Heart and vessels · 2020Article
- A Catastrophic Case of Idiopathic Cholesterol Crystal Embolism with Multiple Lethal Complications: A Labyrinth Underneath the Diagnosis of Skin Ulcers in Chronic Kidney Disease Patients.Internal medicine (Tokyo, Japan) · 2019Article
- A case of anastomotic stenosis of the small intestine caused by cholesterol crystal embolism.Surgical case reports · 2018Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCorticosteroids have been widely used in patients with cholesterol crystal embolism (CCE) and low-density lipoprotein apheresis (LDL-A) was reported to reduce the risk of end-stage renal disease in patients with CCE. This study was designed to evaluate the renoprotective effects of LDL-A in combination with corticosteroids in patients with CCE.
methodsThirty-five patients with CCE who, between 2008 and 2013, had shown renal deterioration after vascular interventions were retrospectively evaluated. All patients received corticosteroids; of these, 24 also received LDL-A and 11 did not, designated LDL-A and control groups, respectively. Differences in eGFR (ΔeGFR), 3 months and 1 year after CCE diagnosis, were compared in the two groups.
resultsThe median estimated glomerular filtration rate (eGFR) in all patients was 38.9 [interquartile range (IQR) 31.9-49.4] ml/min/1.73 m
conclusionsLDL-A plus corticosteroids may restore deteriorated renal function better than corticosteroids alone in patients with CCE.
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