Evidence map›Paper›PMID 27101803›Full record

ArticleAsian journal of andrology

Computer-aided sperm analysis: a useful tool to evaluate patient's response to varicocelectomy.

Julia I Ariagno, Gabriela R Mendeluk, María J Furlan, M Sardi, P Chenlo, Susana M Curi, Mercedes N Pugliese, Herberto E Repetto, Mariano Cohen

Open access · goldAbstract read
In one paragraph

Article in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Julia I AriagnoClinical Biochemistry Department, Male Fertility Laboratory, Faculty of Pharmacy and Biochemetry, University of Buenos Aires, Argentina.
Gabriela R MendelukClinical Biochemistry Department, Male Fertility Laboratory, Faculty of Pharmacy and Biochemetry, University of Buenos Aires, Argentina.
María J FurlanClinical Biochemistry Department, Male Fertility Laboratory, Faculty of Pharmacy and Biochemetry, University of Buenos Aires, Argentina.
M SardiClinical Biochemistry Department, Male Fertility Laboratory, Faculty of Pharmacy and Biochemetry, University of Buenos Aires, Argentina.
P ChenloClinical Biochemistry Department, Male Fertility Laboratory, Faculty of Pharmacy and Biochemetry, University of Buenos Aires, Argentina.
Susana M CuriClinical Biochemistry Department, Male Fertility Laboratory, Faculty of Pharmacy and Biochemetry, University of Buenos Aires, Argentina.
Mercedes N PuglieseClinical Biochemistry Department, Male Fertility Laboratory, Faculty of Pharmacy and Biochemetry, University of Buenos Aires, Argentina.
Herberto E RepettoClinical Biochemistry Department, Male Fertility Laboratory, Faculty of Pharmacy and Biochemetry, University of Buenos Aires, Argentina.
Mariano CohenUrology Department, "José de San Martín" Clinical Hospital, University of Buenos Aires, Buenos Aires, Argentina (CP1120).
University of Buenos Aires · ARHospital de Clínicas "José de San Martín" · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preoperative and postoperative sperm parameter values from infertile men with varicocele were analyzed by computer-aided sperm analysis (CASA) to assess if sperm characteristics improved after varicocelectomy. Semen samples of men with proven fertility (n = 38) and men with varicocele-related infertility (n = 61) were also analyzed. Conventional semen analysis was performed according to WHO (2010) criteria and a CASA system was employed to assess kinetic parameters and sperm concentration. Seminal parameters values in the fertile group were very far above from those of the patients, either before or after surgery. No significant improvement in the percentage normal sperm morphology (P = 0.10), sperm concentration (P = 0.52), total sperm count (P = 0.76), subjective motility (%) (P = 0.97) nor kinematics (P = 0.30) was observed after varicocelectomy when all groups were compared. Neither was significant improvement found in percentage normal sperm morphology (P = 0.91), sperm concentration (P = 0.10), total sperm count (P = 0.89) or percentage motility (P = 0.77) after varicocelectomy in paired comparisons of preoperative and postoperative data. Analysis of paired samples revealed that the total sperm count (P = 0.01) and most sperm kinetic parameters: curvilinear velocity (P = 0.002), straight-line velocity (P = 0.0004), average path velocity (P = 0.0005), linearity (P = 0.02), and wobble (P = 0.006) improved after surgery. CASA offers the potential for accurate quantitative assessment of each patient's response to varicocelectomy.

Indexed as

AdolescentAdultDiagnosis, Computer-AssistedHealthy VolunteersHumansInfertility, MaleMaleMicrosurgeryPostoperative PeriodSemen AnalysisSpermatozoaSperm CountSperm MotilityVaricoceleYoung Adult

Identifiers

PMID27101803
PMCPMC5507091
OpenAlexW2343377098

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.