Evidence map›Paper›PMID 27101409›Full record

ArticlePloS one2016

Enhanced Zone II Flexor Tendon Repair through a New Half Hitch Loop Suture Configuration.

Ioannis Kormpakis, Stephen W Linderman, Stavros Thomopoulos, Richard H Gelberman

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. The cellular basis of fibrotic tendon healing: challenges and opportunities.Translational research : the journal of laboratory and clinical medicine · 2019
    Review
  3. Effect of connective tissue growth factor delivered via porous sutures on the proliferative stage of intrasynovial tendon repair.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2018
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ioannis KormpakisDepartment of Orthopaedic Surgery, Washington University, St. Louis, Missouri, United States of America.
Stephen W LindermanDepartment of Orthopaedic Surgery, Washington University, St. Louis, Missouri, United States of America.ORCID http://orcid.org/0000-0002-1797-5870
Stavros ThomopoulosDepartment of Orthopedic Surgery, Columbia University, New York, New York, United States of America.
Richard H GelbermanDepartment of Orthopaedic Surgery, Washington University, St. Louis, Missouri, United States of America.
Washington University in St. Louis · USColumbia University · US

Funding

NATIONAL RESEARCH SERVICE AWARD-MEDICAL SCIENTISTT32GM007200 · NIGMS · WASHINGTON UNIVERSITY · PI YOKOYAMA, WAYNE M. · 1985 to 2024
$59.8M
The Role of the Osteoblast Secretome in Bone FormationP30AR057235 · NIAMS · WASHINGTON UNIVERSITY · PI ORNITZ, DAVID M · 2009 to 2018
$5.7M
Enhanced Tendon Healing Through Growth Factor and Cell TherapiesR01AR062947 · NIAMS · WASHINGTON UNIVERSITY · PI GELBERMAN, RICHARD H, THOMOPOULOS, STAVROS · 2012 to 2022
$5.5M
Skeletal Disorders Training ProgramT32AR060719 · NIAMS · WASHINGTON UNIVERSITY · PI Roberto Civitelli · 2011 to 2026
$4.6M
Improved orthopaedic repairs through mechanically optimized, adhesive biomaterialsF30AR069491 · NIAMS · WASHINGTON UNIVERSITY · PI LINDERMAN, STEPHEN W · 2016 to 2018
$140k
NIAMS NIH HHS F30 AR069491NIAMS NIH HHS P30 AR057235NIAMS NIH HHS R01 AR062947NIAMS NIH HHS T32 AR060719NIGMS NIH HHS T32 GM007200
6 · The paper itself

Abstract

This study evaluated the impact of a new half hitch loop suture configuration on flexor tendon repair mechanics. Cadaver canine flexor digitorum profundus tendons were repaired with 4- or 8-strands, 4-0 or 3-0 suture, with and without half hitch loops. An additional group underwent repair with half hitch loops but without the terminal knot. Half hitch loops improved the strength of 8-strand repairs by 21% when 4-0, and 33% when 3-0 suture was used, and caused a shift in failure mode from suture pullout to suture breakage. 8-strand repairs with half hitch loops but without a terminal knot produced equivalent mechanical properties to those without half hitch loops but with a terminal knot. 4-strand repairs were limited by the strength of the suture in all groups and, as a result, the presence of half hitch loops did not alter the mechanical properties. Overall, half hitch loops improved repair mechanics, allowing failure strength to reach the full capability of suture strength. Improving the mechanical properties of flexor tendon repair with half hitch loops has the potential to reduce the postoperative risk of gap formation and catastrophic rupture in the early postoperative period.

Indexed as

AnimalsBiomechanical PhenomenaCadaverDogsFemaleRuptureSuture TechniquesTendon InjuriesTensile Strength

Identifiers

PMID27101409
PMCPMC4839582
OpenAlexW2341119717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.