Evidence map›Paper›PMID 27101237›Full record

ArticleJournal of autism and developmental disorders2016

Brief Report: Syndromes in Autistic Children in a Finnish Birth Cohort.

Laura Timonen-Soivio, Raija Vanhala, Heli Malm, Susanna Hinkka-Yli-Salomäki, Mika Gissler, Alan Brown, Andre Sourander

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Characteristics of Autism Spectrum Disorder in Sotos Syndrome.Journal of autism and developmental disorders · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Laura Timonen-SoivioDepartment of Child Psychiatry, University of Turku and Turku University Hospital, Lemminkäisenkatu 3/Teutori, 20014, Turku, Finland. lamtim@utu.fi.
Raija VanhalaDepartment of Child Neurology, Helsinki University Hospital, Helsinki, Finland.
Heli MalmDepartment of Child Psychiatry, University of Turku and Turku University Hospital, Lemminkäisenkatu 3/Teutori, 20014, Turku, Finland.
Susanna Hinkka-Yli-SalomäkiDepartment of Child Psychiatry, University of Turku and Turku University Hospital, Lemminkäisenkatu 3/Teutori, 20014, Turku, Finland.
Mika GisslerDepartment of Child Psychiatry, University of Turku and Turku University Hospital, Lemminkäisenkatu 3/Teutori, 20014, Turku, Finland.
Alan BrownDepartment of Psychiatry, New York State Psychiatric Institute, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Andre SouranderDepartment of Child Psychiatry, University of Turku and Turku University Hospital, Lemminkäisenkatu 3/Teutori, 20014, Turku, Finland.
Columbia University · USUniversity of Turku · FIHelsinki University Hospital · FITurku University Hospital · FIUniversity of Helsinki · FI

Funding

Prenatal factors and risk of autism in a Finnish national birth cohortR01ES019004 · NIEHS · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI BROWN, ALAN STEWART · 2009 to 2017
$3.5M
Epidemiology of Prenatal Factors and Adult PsychopathologyK02MH065422 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BROWN, ALAN STEWART · 2003 to 2012
$1.2M
NIEHS NIH HHS R01 ES019004NIMH NIH HHS K02 MH065422
6 · The paper itself

Abstract

We studied the association between specific congenital syndromes and autism spectrum disorders (ASD) in the large Finnish Register material. Our data include all children diagnosed with ASD (n = 4441) according to Finnish Hospital Discharge Register in 1987-2000. Four controls per each case were matched to sex, birthplace, date of birth (±30 days) and residence in Finland (n = 17,695). The prevalence of specific congenital syndromes in the Finnish Register of Congenital Malformations was evaluated among the ASD group and the controls by sex. The results of this study suggest that there is an association between several etiologically different syndromes and ASD when compared to controls without ASD. Statistically significant associations were observed with 47,XYY, Sotos syndrome, neurofibromatosis I, and syndrome not otherwise specified. Syndromes were more common among males with ASD compared to controls. These results support the previous studies of etiological heterogeneity of ASD and have importance in clinical examination, management and rehabilitation.

Indexed as

AdultAutistic DisorderCase-Control StudiesChildChild, PreschoolCohort StudiesFemaleFinlandHumansMaleNervous System MalformationsPrevalenceRegistriesSyndromeAutism spectrum disorderChromosomal abnormalitiesSingle gene disordersSyndromic autism

Identifiers

PMID27101237
OpenAlexW2339576241

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.