ArticlePloS one2016
Childhood Tuberculosis in a Sub-Saharan Tertiary Facility: Epidemiology and Factors Associated with Treatment Outcome.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Performance of adenosine deaminase in detecting paediatric pleural tuberculosis: a systematic review and meta-analysis.Annals of medicine · 2022Pooled it
- Tuberculosis Treatment Outcome and Predictors in Africa: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- High levels of unfavourable treatment outcomes in children with drug-sensitive TB in Sierra Leone.Public health action · 2026Article
- Spatial distribution of paediatric tuberculosis and factors associated with adverse treatment outcomes in Ashanti Region, Ghana: a retrospective analysis.BMC pediatrics · 2025Article
- Clinical and radiological profile of tuberculosis and treatment outcome in patients ≤18 years: A prospective study.Journal of family medicine and primary care · 2025Article
- Changes in The Trends of Tuberculosis-related Indicators in Hamadan Province Using the Join Point Regression Approach From 2011 to 2022.Journal of research in health sciences · 2025Article
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- Epidemiology of childhood tuberculosis and predictors of death among children on tuberculosis treatment in central Ethiopia: an extended Cox model challenged survival analysis.BMC public health · 2023Article
- The Spectrum of Childhood Tuberculosis in an African Setting: A Hospital-Based Experience in Bamenda, Cameroon.Turkish archives of pediatrics · 2023Article
- Epidemiology of Pediatric Tuberculosis and Factors Associated with Unsuccessful Treatment Outcomes in the Centre Region of Cameroon: A Three-Year Retrospective Cohort Study.Interdisciplinary perspectives on infectious diseases · 2022Article
- Treatment outcome of pediatric tuberculosis in eastern Ethiopia.Frontiers in pediatrics · 2022Article
- Serum-Based Diagnosis of Pediatric Tuberculosis by Assay of Mycobacterium tuberculosis Factors: a Retrospective Cohort Study.Journal of clinical microbiology · 2021Article
- Clinical spectrum of childhood tuberculosis and outcome at Mohammed Alamin Hamid Pediatric Hospital, Omdurman, Sudan.Sudanese journal of paediatrics · 2021Article
- Characteristics of paediatric patients with tuberculosis and associated determinants of treatment success in Malaysia using the MyTB version 2.1 database over five years.BMC public health · 2020Article
- Treatment delay in childhood pleural tuberculosis and associated factors.BMC infectious diseases · 2020Article
- Epidemiological Trends in the Form of Childhood Tuberculosis in a Referral Tuberculosis Hospital in Shandong, China.BioMed research international · 2020Article
- Declining Trends in Childhood TB Notifications and Profile of Notified Patients in the City of Harare, Zimbabwe, from 2009 to 2018.Journal of tropical medicine · 2020Article
- Childhood tuberculosis treatment outcome and its association with HIV co-infection in Ethiopia: a systematic review and meta-analysis.Tropical medicine and health · 2020Review
- Childhood tuberculosis and treatment outcomes in Accra: a retrospective analysis.BMC infectious diseases · 2019Article
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Childhood tuberculosis (TB) is a diagnostic challenge in developing countries, and patient outcome can be influenced by certain factors. We report the disease course, clinical profile and factors associated with treatment outcome in a tertiary facility of Kinshasa. Documentary and analytical studies were conducted using clinical and exploratory data for children aged up to 15 years who were admitted to the University Clinics of Kinshasa for TB. Data are presented as frequencies and averages, and binary and logistic regression analyses were performed. Of 283 children with TB, 82 (29.0%) had smear-negative TB, 40 (14.1%) had smear-positive TB, 159 (56.1%) had extra-pulmonary TB (EPTB), 2 (0.7%) had multidrug-resistant TB (MDR-TB), 167 (59.0%) completed treatment, 30 (10.6%) were cured, 7 (2.5%) failed treatment, 4 (1.4%) died, 55 (19.4%) were transferred to health centers nearest their home, and 20 (7.0%) were defaulters. In the binary analysis, reported TB contacts (p = 0.048), type of TB (p = 0.000), HIV status (p = 0.050), Ziehl-Nielsen test result (p = 0.000), Lowenstein culture (p = 0.004) and chest X-ray (p = 0.057) were associated with outcome. In the logistic regression, none of these factors was a significant predictor of outcome. Tertiary level care facilities must improve the diagnosis and care of patients with childhood TB, which justifies the development of alternative diagnostic techniques and the assessment of other factors that potentially affect outcome.
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