SynthesisPloS one2016
Systematic Review and Meta-Analysis on Incidence of Altered Sensation of Mandibular Implant Surgery.
Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05659069 (The Effect of Inferior Alveolar Nerve Lateralization on Nutritional Status, Masticatory Performance and Speech; Observational Study), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Inferior Alveolar Nerve Lateralization on Nutritional Status, Masticatory Performance and Speech; Observational Study
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Inferior alveolar nerve damage related to dental implant placement. A systematic review and meta-analysis.Medicina oral, patologia oral y cirugia bucal · 2025Pooled it
- Prevalence and management of neuropathic injury caused by dental implant insertion in mandible: a systematic review.Journal of oral & facial pain and headache · 2024Pooled it
- Photobiomodulation for the management of inferior alveolar nerve paresthesia after implant surgery: A randomized clinical trial.Medicina oral, patologia oral y cirugia bucal · 2026Trial
- Modified Neumann incision for implant placement in overdentures: Case series of a less invasive alternative.Clinical advances in periodontics · 2026Article
- Evaluation of the Effects of Implants with Different Geometries on the Inferior Alveolar Nerve Under Occlusal Stresses.Journal of functional biomaterials · 2026Article
- Reliability of the AI-Assisted Assessment of the Proximity of the Root Apices to Mandibular Canal.Journal of clinical medicine · 2024Article
- Article
- Morphological and topographic evaluation of the mandibular canal and its relationship with the facial profile, skeletal class, and sex.Oral and maxillofacial surgery · 2023Article
- TRPV4 Role in Neuropathic Pain Mechanisms in Rodents.Antioxidants (Basel, Switzerland) · 2022Review
- Persistent, neuropathic-like trigeminal pain after dental implant loading.Journal of clinical and experimental dentistry · 2022Article
- Effect of vitamin B complex administration on pain and sensory problems related to inferior alveolar nerve damage following mandibular implant placement surgery.Journal of advanced periodontology & implant dentistry · 2022Article
- CBCT Evaluation of Buccolingual Orientation of Inferior Alveolar Canal in Mandibular Posterior Region for Implant Planning.International journal of dentistry · 2022Article
- Trigeminal nerve injuries. Four years' experience at a single Argentine referral center and a literature review.Acta odontologica latinoamericana : AOL · 2021Review
- Injuries of the Peripheral Mandibular Nerve, Evaluation of Interventions and Outcomes: A Systematic Review.Craniomaxillofacial trauma & reconstruction · 2021Review
- Oxytocin-Dependent Regulation of TRPs Expression in Trigeminal Ganglion Neurons Attenuates Orofacial Neuropathic Pain Following Infraorbital Nerve Injury in Rats.International journal of molecular sciences · 2020Article
- Laser therapy as treatment for oral paresthesia arising from mandibular third molar extraction.Journal of clinical and experimental dentistry · 2020Article
- Increase in IGF-1 Expression in the Injured Infraorbital Nerve and Possible Implications for Orofacial Neuropathic Pain.International journal of molecular sciences · 2019Article
- The Anatomical Nature of Dental Paresthesia: A Quick Review.The open dentistry journal · 2018Review
- Macrophages in trigeminal ganglion contribute to ectopic mechanical hypersensitivity following inferior alveolar nerve injury in rats.Journal of neuroinflammation · 2017Article
- Sensory Changes Related to Dental Implant Placement: A Scoping Review.Journal of oral & facial pain and headacheArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Altered sensation (including paresthesia, dysesthesia and hypoesthesia) after mandibular implant surgery may indicate transient or permanent injury of the inferior alveolar nerve and the mental branch, and considerably lower patients' satisfaction about the therapy. Previous studies have shown a great degree of variability on the incidence of altered sensation. We here reported the incidence of altered sensation after mandibular implant surgery based on a meta-analysis of 26 articles published between 1990.1.1 and 2016.1.1. Study quality and risk of bias was assessed and the studies with a lower score were excluded in the meta-analysis. Data synthesis was performed using the logistic-normal random-effect model. The meta-analyses revealed that the short-term (10 days after implant placement) and long-term (1 year after implant placement) incidence was 13% (95% CI, 6%-25%) and 3% (95% CI, 1%-7%), respectively. (2) For the patients who initially reported altered sensation, 80% (95% CI, 52%-94%) of them would return to normal sensation within 6 months after surgery, and 91% (95% CI, 78%-96%) of them would return to normal sensation one year after surgery. We concluded that dentist-patient communication about the risk of altered sensation is critical to treatment planning, since the short-term incidence of altered sensation is substantial (13%). When a patient reports altered sensation, regular assessment for 6 months would help tracing the changes of symptoms. In terms of long-term follow-up (1 year after surgery), the incidence is much lower (3%) and most patients (91%) would return to normal sensation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.