ArticleJournal of the American Geriatrics Society2016
Trends in Prevalence and Determinants of Potentially Inappropriate Prescribing in the United States: 2007 to 2012.
Article in Journal of the American Geriatrics Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Factors associated with potentially inappropriate medication use in community-dwelling older adults in the United States: a systematic review.The International journal of pharmacy practice · 2019Pooled it
- Trial
- Potentially inappropriate medications for geriatric patients in Bahrain: prevalence, predictors, and implications for practice.BMC geriatrics · 2025Article
- Addressing the need for standardization of symptomatic medication documentation in Parkinson's disease clinical research: A call to action.Journal of Parkinson's disease · 2025Review
- Enhancing medication appropriateness: Insights from the STOPP (Screening Tool of Older Persons' Prescriptions) criteria version 3 on prescribing practices among the older adults in Pakistan.Frontiers in pharmacology · 2025Article
- Associations between sex, race/ethnicity, and age and the initiation of chronic high-risk medication in US older adults.Journal of the American Geriatrics Society · 2024Article
- Racial and ethnic disparities in potentially inappropriate medication use in patients with dementia.Journal of the American Geriatrics Society · 2024Article
- Validating claims-based definitions for deprescribing: Bridging the gap between clinical and administrative data.Pharmacoepidemiology and drug safety · 2024Article
- Potentially Inappropriate Medications in Older Adults-Prevalence, Trends and Associated Factors: A Cross-Sectional Study in Saudi Arabia.Healthcare (Basel, Switzerland) · 2023Article
- Regional variations in excessive polypharmacy and potentially inappropriate drug use among older adults in Sweden: Trends from 2006 to 2020.Frontiers in pharmacology · 2023Article
- Association of potentially inappropriate medications and need for long-term care among older adults: a matched cohort study.BMC geriatrics · 2022Article
- Potentially inappropriate medication use by level of polypharmacy among US Veterans 49-64 and 65-70 years old.Pharmacoepidemiology and drug safety · 2022Article
- Potentially Inappropriate Prescribing among Elderly Outpatients: Evaluation of Temporal Trends 2012-2018 in Piedmont, Italy.International journal of environmental research and public health · 2022Article
- Risk of Potentially Inappropriate Medications in Adults With CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2021Observational
- Prevalence and Determinants of Multimorbidity, Polypharmacy, and Potentially Inappropriate Medication Use in the Older Outpatients: Findings from EuroAgeism H2020 ESR7 Project in Ethiopia.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Are there sex differences in potentially inappropriate prescribing in adults with multimorbidity?Journal of the American Geriatrics Society · 2021Article
- Prevalence and determinants of potentially inappropriate medication use in Hong Kong older patients: a cross-sectional study.BMJ open · 2021Article
- Trends in polypharmacy and potentially inappropriate medication (PIM) in older and middle-aged people treated for diabetes.British journal of clinical pharmacology · 2021Article
- Comparison of adaptive versions of the Hong Kong-specific criteria and 2015 Beers criteria for assessing potentially inappropriate medication use in Hong Kong older patients.BMC geriatrics · 2021Article
- Patient- and Prescriber-Related Factors Associated with Potentially Inappropriate Medications and Drug-Drug Interactions in Older Adults.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectivesTo estimate the prevalence and determinants of the use of potentially inappropriate medications (PIMs) in older U.S. adults using the 2012 Beers criteria.
designRetrospective cohort study in a random national sample of Medicare beneficiaries.
settingFee-for-service Medicare beneficiaries from 2007 to 2012.
participantsU.S. population aged 65 and older with Parts A, B, and D enrollment in at least 1 month during a calendar year (N = 38,250 individuals; 1,308,116 observations). MEASUREMENTS: The 2012 Beers criteria were used to estimate the prevalence of the use of PIMs in each calendar month and over a 12-month period using data on diagnoses or conditions present in the previous 12 months. Generalized estimating equations were used to account for the dependence of multiple monthly observations of a single person when estimating 95% confidence intervals (CIs), and logistic regression was used to identify independent determinants of PIM use.
resultsThe point prevalence of the use of PIMs decreased from 37.6% (95% CI = 37.0-38.1) in 2007 to 34.2% (95% CI = 33.6-34.7) in 2012, with a statistically significant 2% (95% CI = 1-3%) decline per year assuming a linear trend. The 1-year period prevalence declined from 64.9% in 2007 to 56.6% in 2012. The strongest predictor of PIM use was the number of drugs dispensed. Individuals aged 70 and older and those seen by a geriatrician were less likely to receive a PIM.
conclusionFrom 2007 to 2012, the prevalence of PIM use in older U.S. adults decreased according to the 2012 Beers criteria, although it remains high, still affecting one-third each month and more than half over 12 months. The number of dispensed prescriptions could be used to target future interventions.
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