ArticleAddictive behaviors2016
Directions of the relationship between substance use and depressive symptoms from adolescence to young adulthood.
Article in Addictive behaviors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- Cannabis and Cannabinoids in Mood and Anxiety Disorders: Impact on Illness Onset and Course, and Assessment of Therapeutic Potential.The American journal on addictions · 2020Pooled it
- Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood: A Systematic Review and Meta-analysis.JAMA psychiatry · 2019Pooled it
- Epigenetics of generalized internet use disorder including data on overuse of social media: a closer look at the SLC6A4, NR3C1 and OXT genes.BMC psychiatry · 2026Article
- Exploring the Role of Ethnic Identity, Attachment, and Family Prosocial Opportunities on BIPOC Adolescents' Anxiety and Depression.Journal of racial and ethnic health disparities · 2026Article
- Cultural adaptation of evidence-based prevention programs for substance use and mental health issues in adolescents: a qualitative secondary analysis of barriers and facilitators.Translational behavioral medicine · 2026Article
- Cross-sectional and longitudinal influences of stress mindset on adolescent depressive symptoms and cannabis use.Anxiety, stress, and coping · 2025Article
- Neighborhood Social Processes and Adolescents' Depressive Symptoms: The Intervening Role of Neighborhood Self-Efficacy.Journal of community psychology · 2025Article
- Substance Use-Related Factors and Recurrent Depression among Former Adolescent Psychiatric Inpatients.European addiction research · 2025Article
- Development of Comorbid Alcohol Use and Depressive Symptoms During Late Adolescence: Examining the Roles of Emotion Regulation and Gender Differences.Research on child and adolescent psychopathology · 2024Article
- The therapeutic alliance in blended versus face-to-face cognitive behavioral therapy for adolescents and young adults with a depressive disorder.Internet interventions · 2024Article
- Depression screening outcomes among adolescents, young adults, and adults reporting past 30-day tobacco and cannabis use.Addictive behaviors · 2024Article
- Examining temporal trends in psychological distress and the co-occurrence of common substance use in a population-based sample of grade 7-12 students from 2013 to 2019.Social psychiatry and psychiatric epidemiology · 2024Article
- Cannabis use among adolescents and young adults during the COVID-19 pandemic: A systematic review.Drug and alcohol dependence reports · 2024Review
- Race/ethnic differences in the association of anxiety, depression, and discrimination with subsequent nicotine and cannabis use among young adults: A prospective longitudinal study.Addictive behaviors · 2024Article
- A latent class approach to understanding patterns of emotional and behavioral problems among early adolescents across four low- and middle-income countries.Development and psychopathology · 2023Article
- Article
- Bidirectional associations between depressive symptoms and cigarette, e-cigarette, cannabis, and alcohol use: Cross-lagged panel analyses among young adults before and during COVID-19.Addictive behaviors · 2022Article
- Weighing the Risk: Developmental Pathways and Processes Underlying Obesity to Substance Use in Adolescence.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2022Review
- The Link Between Depressive Symptoms and Vaping Nicotine in U.S. Adolescents, 2017-2019.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2022Article
- Childhood adversities and mental health outcomes: Does the perception or age of the event matter?Development and psychopathology · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
purposeBoth substance use and depression are common in adolescence and often comorbid. Past research has produced conflicting results on whether there is a temporal relationship and if so, in which direction it operates and how it may vary by sex. The purpose of this paper is to explore the longitudinal, potentially bidirectional, relationships between high-frequency substance use and depressive symptoms from adolescence into young adulthood for males and females.
methodsUsing data from the National Longitudinal Study of Adolescent to Adult Health we investigated longitudinal associations between high frequency substance use (alcohol, cigarettes, and marijuana) and depressive symptoms. The linear mixed effects models were stratified by sex and used a lagged measure of the dependent variable to test temporal relationships. A random intercept was used for respondent ID.
resultsIncreases in depressive symptoms were significantly associated with a later increase of about a half day in marijuana use frequency for males and nearly a two day increase in smoking frequency for females. Conversely, increases in smoking frequency were significantly associated with approximately a 0.6-point increase for females and 0.4-point increase for males in depressive symptoms at a later wave.
conclusionsResults indicate a bidirectional relationship between smoking and depressive symptoms for females. For males, there was evidence supporting self-medication with marijuana and for smoking being associated with later increases in depressive symptoms. Results inform how substance use and depression screening, prevention and treatment efforts should be paired and targeted for males and females.
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