Evidence map›Paper›PMID 27100437›Full record

Observational studyMedicine2016

Development of the A-DIVA Scale: A Clinical Predictive Scale to Identify Difficult Intravenous Access in Adult Patients Based on Clinical Observations.

Fredericus H J van Loon, Lisette A P M Puijn, Saskia Houterman, Arthur R A Bouwman

4 registry-linked trialsAbstract readObservational Study
In one paragraph

Observational study in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 37 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03932214 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Infrared Illumination for Difficult Peripheral Venous Catheterization in Adult Critically-ill Patients

TypeinterventionalSponsorAssistance Publique - Hôpitaux de ParisRan2019 to 2025Enrolled460ConditionsPeripheral Venous CatheterizationArmsACCUVEIN
NCT04262947 naterminatednot on this mapstarted 2020, after this paper: background citation

The Efficacy of Near-Infrared Vein Imaging for the Success of Placing Peripheral Venous Catheters in Adults With Difficult Venous Access

TypeinterventionalSponsorLahey ClinicRan2020 to 2020Enrolled38ConditionsCatheterization, PeripheralArmsNear Infrared Vein Imaging, Conventional IV placement
NCT05935228 narecruitingnot on this mapstarted 2023, after this paper: background citation

Development and Evaluation of an Algorithm for Vascular Access Management - ALCOV Pilot Study

TypeinterventionalSponsorCentral Hospital, Nancy, FranceRan2023 to 2027Enrolled794ConditionsPeripheral Venous AccessArmsImplementation of the A-DIVA Scale, Implementation of the algorithm composed of the A-DIVA Scale and the new decision-making tree (the A-DIVA Tool) in the centers
NCT07629427 nacompletednot on this mapstarted 2026, after this paper: background citation

A Comparison of 18-Gauge and 20-Gauge Intravenous Cannulas in Terms of Pain and Procedural Difficulty: A Randomized Controlled Trial in the Emergency Department

TypeinterventionalSponsorMarmara University Pendik Training and Research HospitalRan2026 to 2026Enrolled204ConditionsPeripheral Catheterization, Veins, Emergency Department Patient, PainArms18-gauge peripheral intravenous cannula, 20-gauge peripheral intravenous cannula
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  13. Reality and challenges of peripheral vascular access: a mixed-methods study.International journal of nursing studies advances · 2026
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  20. Evaluation of the Efficiency of the Newly Developed Needle in Emergency Room: A Single-Center Observational Study.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fredericus H J van LoonFrom the Department of Anesthesiology (FHJL, LAPMP, ARAB), Catharina Hospital Eindhoven, The Netherlands; Department of Research and Education (FHJL, SH), Catharina Hospital Eindhoven, The Netherlands; Fontys University of Applied Sciences (FHJL), Eindhoven, The Netherlands; Department of Signal Processing Systems and Electrical Enginereering (ARAB), TU/e University of Technology, Eindhoven, The Netherlands.
Lisette A P M Puijn
Saskia Houterman
Arthur R A Bouwman

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Placement of a peripheral intravenous catheter is a routine procedure in clinical practice, but failure of intravenous cannulation regularly occurs. An accurate and reliable predictive scale for difficult venous access creates the possibility to use other techniques in an earlier time frame. We aimed to develop a predictive scale to identify adult patients with a difficult intravenous access prospectively: the A-DIVA scale. This prospective, observational, cross-sectional cohort study was conducted between January 2014 and January 2015, and performed at the department of anesthesiology of the Catharina Hospital (Eindhoven, The Netherlands). Patients 18 years or older were eligible if scheduled for any surgical procedure, regardless ASA classification, demographics, and medical history. Experienced and certified anesthesiologists and nurse anesthetists routinely obtained peripheral intravenous access. Cannulation was performed regarding standards for care. A failed peripheral intravenous cannulation on the first attempt was the outcome of interest. A population-based sample of 1063 patients was included. Failure of intravenous cannulation was observed in 182/1063 patients (17%). Five variables were associated with a failed first attempt of peripheral intravenous cannulation: palpability of the target vein (OR = 4.94, 95% CI [2.85-8.56]; P < 0.001), visibility of the target vein (OR = 3.63, 95% CI [2.09-6.32]; P < 0.001), a history of difficult peripheral intravenous cannulation (OR = 3.86, 95% CI [2.39-6.25]; P < 0.001), an unplanned indication for surgery (OR = 4.86, 95% CI [2.92-8.07]; P < 0.001), and the vein diameter of at most 2 millimeters (OR = 3.37, 95% CI [2.12-5.36]; P < 0.001). The scoring system was applied in 3 risk groups: 36/788 patients (5%) suffered from a failed first attempt in the low-risk group (A-DIVA score 0 or 1), whereas the medium (A-DIVA score 2 or 3) and high-risk group (A-DIVA score 4 plus), included 72/195 (37%) and 74/80 (93%) patients with a failed first attempt of inserting a peripheral intravenous catheter, respectively. The additive 5-variable A-DIVA scale is a reliable predictive rule that implies the probability to identify patients with a difficult intravenous access prospectively. Dutch Trial Register (ref: 4595).

Indexed as

Decision Support TechniquesAdultCatheterization, PeripheralCross-Sectional StudiesEmergenciesEmergency Service, HospitalFemaleFollow-Up StudiesHumansMaleMiddle AgedMorbidityNetherlandsProspective StudiesRisk FactorsROC Curve

Identifiers

PMID27100437
PMCPMC4845841

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.