Trial reportMedicine2016
Rapid Infancy Weight Gain and 7- to 9-year Childhood Obesity Risk: A Prospective Cohort Study in Rural Western China.
Trial report in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- The Effect of Growth Rate during Infancy on the Risk of Developing Obesity in Childhood: A Systematic Literature Review.Nutrients · 2021Pooled it
- Rapid weight gain during infancy and subsequent adiposity: a systematic review and meta-analysis of evidence.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2018Pooled it
- Gestational diabetes detection thresholds and infant growth, nutrition, and neurodevelopment at 12-18 months: a prospective cohort study within a randomized trial.Journal of perinatology : official journal of the California Perinatal Association · 2025Trial
- Multifaceted approaches to promoting the growth potential in small-for-gestational-age infants and their clinical relevance.Pakistan journal of medical sciences · 2025Article
- The Accumulative Effect of Multiple Postnatal Risk Factors with the Risk of Being Overweight/Obese in Late Childhood.Nutrients · 2024Article
- [Longitudinal study on catch-up growth in preterm infants with small for gestational age at corrected ages 0-24 months].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Article
- Association of Maternal BMI and Rapid Infant Weight Gain With Childhood Body Size and Composition.Pediatrics · 2023Article
- Faster rehabilitation weight gain during childhood is associated with risk of non-communicable disease in adult survivors of severe acute malnutrition.PLOS global public health · 2023Article
- Constructing a polygenic risk score for childhood obesity using functional data analysis.Econometrics and statistics · 2023Article
- Article
- Adherence to supplemental vitamin D intake and infant weight gain: a retrospective cohort study in rural southwestern China.The Journal of international medical research · 2020Article
- Parental Self-Efficacy in New Mothers Predicts Infant Growth Trajectories.Western journal of nursing research · 2020Article
- Body composition during early infancy and its relation with body composition at 4 years of age in Jimma, an Ethiopian prospective cohort study.Nutrition & diabetes · 2018Article
- Prevalence and factors associated with overweight and obesity among children from primary schools in urban areas of Lomé, Togo.Public health nutrition · 2018Article
- Associations between gestational weight gain and rate of infancy weight gain in Hawai'i and Puerto Rico WIC participants.BMC obesity · 2018Article
- Association between Sleep and Body Weight: A Panel Data Model Based on a Retrospective Longitudinal Cohort of Chinese Infants.International journal of environmental research and public health · 2017Article
- Early life gut microbiota is associated with rapid infant growth in Hispanics from Southern California.Gut microbesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is increasing in developing countries. This study aimed to identify the association between rapid infancy weight gain and obesity risk among early school-age children. A total of 581 singletons (349 boys, 232 girls) whose mothers participated in an antenatal multiple micronutrient supplement trial in rural western China were followed from birth to between 7 and 9 years of age. Height and weight were measured at birth, 1.5 years, and between 7 and 9 years. At the 7- to 9-year time point, body composition was determined using bioelectrical impedance analysis. Multilevel mixed analysis was used to test the associations between rapid weight gain in infancy (from birth to age 1.5 years) and body size and composition or overweight/obesity among early school-age children. Overall, 31.2% (181 of 581) of the infants showed a weight-for-age Z score gain greater than 0.67 between birth and 1.5 years, indicating rapid weight gain. Approximately 5.7% (33 of 579) of the subjects were overweight (BMI-for-age Z scores [BAZ] >1 and ≤2) or obese (BAZ >2). Rapid infancy weight gain was associated with a higher BAZ (P < 0.001), mid-upper arm circumferences (P < 0.001), percentage body fat (P < 0.001), and fat mass index (P < 0.001) at 7 to 9 years of age after adjusting for biological and social economic factors, genetic factors, and perinatal and postnatal factors. These associations appeared to be independent of gender, economic status at early school age, and maternal nutritional status at enrollment. Rapid growers may have approximately 3 times the risk of being overweight/obese during the early school-age years (odds ratio = 2.94, 95% CI: 1.17-7.43, P = 0.022). Rapid infancy weight gain is a risk factor for being overweight/obesity among early school-age children in rural western China. We propose that social and biological determinants, such as economic status, physical activity, and feeding practice, should be targeted to prevent obesity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.