ReviewAnalytical and bioanalytical chemistry2016
Application of whole genome shotgun sequencing for detection and characterization of genetically modified organisms and derived products.
Review in Analytical and bioanalytical chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 51 citations in OpenAlex.
- Read-mapping signatures for molecular characterization of transgenic DNA insertions in paired-end Illumina data.BMC biotechnology · 2026Article
- Next-generation sequencing: A powerful multi-purpose tool in cell line development for biologics production.Computational and structural biotechnology journal · 2025Review
- Targeted High-Throughput Sequencing Enables the Detection of Single Nucleotide Variations in CRISPR/Cas9 Gene-Edited Organisms.Foods (Basel, Switzerland) · 2023Article
- Plant microbe based remediation approaches in dye removal: A review.Bioengineered · 2022Review
- An optimized procedure for detection of genetically modified DNA in refined vegetable oils.Food science and biotechnology · 2021Article
- Targeted MinION sequencing of transgenes.Scientific reports · 2020Article
- Sequencing of two transgenic early-flowering poplar lines confirmed vector-free single-locus T-DNA integration.Transgenic research · 2020Article
- Detection and identification of transgenic events by next generation sequencing combined with enrichment technologies.Scientific reports · 2019Article
- Identification of T-DNA Insertion Site and Flanking Sequence of a Genetically Modified Maize Event IE09S034 Using Next-Generation Sequencing Technology.Molecular biotechnology · 2019Article
- Detection of Protein Toxin Simulants from Contaminated Surfaces by Paper Spray Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2019Article
- A high-throughput and ultrasensitive identification methodology for unauthorized GMP component based on suspension array and logical calculator.Scientific reports · 2019Article
- Safety Assessment of Genetically Modified Feed: Is There Any Difference From Food?Frontiers in plant science · 2019Review
- Detection and Identification of Genome Editing in Plants: Challenges and Opportunities.Frontiers in plant science · 2019Article
- Critical assessment of digital PCR for the detection and quantification of genetically modified organisms.Analytical and bioanalytical chemistry · 2018Review
- Nanopore sequencing technology: a new route for the fast detection of unauthorized GMO.Scientific reports · 2018Article
- The use of targeted genomic capture and massively parallel sequencing in diagnosis of Chinese Leukoencephalopathies.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The emergence of high-throughput, massive or next-generation sequencing technologies has created a completely new foundation for molecular analyses. Various selective enrichment processes are commonly applied to facilitate detection of predefined (known) targets. Such approaches, however, inevitably introduce a bias and are prone to miss unknown targets. Here we review the application of high-throughput sequencing technologies and the preparation of fit-for-purpose whole genome shotgun sequencing libraries for the detection and characterization of genetically modified and derived products. The potential impact of these new sequencing technologies for the characterization, breeding selection, risk assessment, and traceability of genetically modified organisms and genetically modified products is yet to be fully acknowledged. The published literature is reviewed, and the prospects for future developments and use of the new sequencing technologies for these purposes are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.