Evidence map›Paper›PMID 27100191›Full record

ArticleNeuron2016

Mind the Gap Junctions: The Importance of Electrical Synapses to Visual Processing.

Jonathan B Demb, Joshua H Singer

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuron, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Network Architecture of Gap Junctional Coupling among Parallel Processing Channels in the Mammalian Retina.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Jonathan B DembDepartment of Ophthalmology and Visual Science, Yale University, New Haven, CT 06511, USA; Department of Cellular and Molecular Physiology, Yale University, New Haven, CT 06511, USA. Electronic address: jonathan.demb@yale.edu.
Joshua H SingerDepartment of Biology, University of Maryland, College Park, MD 20742, USA. Electronic address: jhsinger@umd.edu.

Funding

Synaptic Transmission in The Rod Pathway of the Mammalian RetinaR01EY017836 · NEI · UNIV OF MARYLAND, COLLEGE PARK · PI Jonathan B Demb, Anastas Popratiloff · 2007 to 2026
$7.2M
CRCNS: Biophysical properties of parallel neural circuits serving night visionR01EY021372 · NEI · UNIV OF MARYLAND, COLLEGE PARK · PI DEMB, JONATHAN B, SINGER, JOSHUA H · 2010 to 2016
$2.1M
NEI NIH HHS R01 EY017836NEI NIH HHS R01 EY021372
6 · The paper itself

Abstract

In this issue of Neuron, Kuo et al. (2016) show that coordinated interaction between electrical and chemical synapses in a defined retinal circuit enhances sensitivity to moving objects. Their work demonstrates how electrical and chemical synapses combine to improve information processing in a specific area of the CNS.

Indexed as

Electrical SynapsesGap JunctionsHumansNeuronsRetinaSynapses

Identifiers

PMID27100191
PMCPMC5751935

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.