Evidence map›Paper›PMID 27099868›Full record

ArticleAIMS environmental science

Traffic-related air pollution and brain development.

Nicholas Woodward, Caleb E Finch, Todd E Morgan

Open access · goldAbstract read
In one paragraph

Article in AIMS environmental science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Relation of prenatal and postnatal PMInternational journal of hygiene and environmental health · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. COVID-19, crisis, and emotional stress: A biocultural perspective of their impact on growth and development for the next generation.American journal of human biology : the official journal of the Human Biology Council · 2020
    Review
  8. Air Pollution and Emergency Department Visits for Mental Disorders among Youth.International journal of environmental research and public health · 2020
    Article
  9. Article
  10. Review
  11. Article
  12. Particle toxicology and health - where are we?Particle and fibre toxicology · 2019
    Review
  13. Review
  14. Article
  15. Air pollution and Autism in Denmark.Environmental epidemiology (Philadelphia, Pa.) · 2018
    Article
  16. Maternal Exposure to PMInternational journal of molecular sciences · 2018
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nicholas WoodwardDavis School of Gerontology and the Dornsife College, Department of Biological Sciences, University of Southern California, 3715 McClintock Ave, Los Angeles CA 9009-0191, USA.
Caleb E FinchDavis School of Gerontology and the Dornsife College, Department of Biological Sciences, University of Southern California, 3715 McClintock Ave, Los Angeles CA 9009-0191, USA.
Todd E MorganDavis School of Gerontology and the Dornsife College, Department of Biological Sciences, University of Southern California, 3715 McClintock Ave, Los Angeles CA 9009-0191, USA.
University of Southern California · US

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Joseph Leo Wiemels · 1996 to 2026
$46.4M
RESEARCH TRAINING IN GERONTOLOGYT32AG000037 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE, EILEEN M CRIMMINS · 1985 to 2026
$13.2M
Air Pollution and vulnerability to Alzheimer-like neurodegeneration in miceR21AG040683 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FINCH, CALEB E · 2011 to 2012
$365k
Aging and sensitivity to traffic-generated air pollutants in male and female miceR21AG040753 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FINCH, CALEB E · 2011 to 2012
$365k
NIA NIH HHS R21 AG040683NIA NIH HHS R21 AG040753NIA NIH HHS T32 AG000037NIEHS NIH HHS P30 ES007048
6 · The paper itself

Abstract

Automotive traffic-related air pollution (TRP) imposes an increasing health burden with global urbanization. Gestational and early child exposure to urban TRP is associated with higher risk of autism spectrum disorders and schizophrenia, as well as low birth weight. While cardio-respiratory effects from exposure are well documented, cognitive effects are only recently becoming widely recognized. This review discusses effects of TRP on brain and cognition in human and animal studies. The mechanisms underlying these epidemiological associations are studied with rodent models of pre- and neonatal exposure to TRP, which show persisting inflammatory changes and altered adult behaviors and cognition. Some behavioral and inflammatory changes show male bias. Rodent models may identify dietary and other interventions for neuroprotection to TRP.

Indexed as

body weightbraininflammationPM2.5prenataltraffic-related air pollutionultrafine PM

Identifiers

PMID27099868
PMCPMC4835031
OpenAlexW1950878272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.