Evidence map›Paper›PMID 27099758›Full record

ArticleBMJ open respiratory research2016

Effects of body mass index, tobacco smoking, alcohol drinking and solid fuel use on the risk of asthma: Individual Participant Data (IPD) meta-analysis of 175 000 individuals from 51 nationally representative surveys.

Jayadeep Patra, Yurie Izawa Maher, Sujata Mishra, Mehak Bhatia, Dewan Alam, Doki S Malini, Prakash C Gupta, Prabhat Jha

Open access · goldAbstract read
In one paragraph

Article in BMJ open respiratory research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Asthma interactions between obesity and other risk factors.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Jayadeep PatraCentre for Global Health Research, St Michael's Hospital, Toronto, Ontario, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Yurie Izawa MaherCentre for Global Health Research, St Michael's Hospital , Toronto, Ontario , Canada.
Sujata MishraCentre for Global Health Research, St Michael's Hospital , Toronto, Ontario , Canada.
Mehak BhatiaCentre for Global Health Research, St Michael's Hospital , Toronto, Ontario , Canada.
Dewan AlamCentre for Global Health Research, St Michael's Hospital , Toronto, Ontario , Canada.
Doki S MaliniDepartment of Community Medicine , MKCG Medical College , Berhampur, Orissa , India.
Prakash C GuptaHealis-Sekhsaria Institute of Public Health , Navi Mumbai, Maharashtra , India.
Prabhat JhaCentre for Global Health Research, St Michael's Hospital, Toronto, Ontario, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
St. Michael's Hospital · CAPublic Health Ontario · CACentre for Global Health Research · CAInstitute of Public Health · INMaharaja Krishna Chandra Gajapati Medical College and Hospital · IN

Funding

Strengthening monitoring of Indian tobacco mortalityR01TW005991 · FIC · ST. MICHAEL'S HOSPITAL · PI JHA, PRABHAT · 2002 to 2006
$862k
Measuring Tobacco Mortality within the Million Death Study in IndiaR01TW007939 · FIC · ST. MICHAEL'S HOSPITAL · PI JHA, PRABHAT · 2007 to 2010
$540k
FIC NIH HHS R01 TW005991FIC NIH HHS R01 TW007939
6 · The paper itself

Abstract

backgroundWe assessed the relationship of body mass index (BMI), smoking, drinking and solid fuel use (r; SFU), and the individual and combined effects of these factors on wheezing symptoms (WS) and on diagnosed asthma (DA).

methodsWe analysed 175 000 individuals from 51 nationally representative surveys, using self-reports of WS and DA as the measures of asthma. The fixed-effects and random-effects estimates of the pooled ORs between asthma and underweight (BMI <18.5 kg/m(2)), obesity (BMI ≥30 kg/m(2)), smoking, drinking and SFU were reported.

resultsThe pooled risks of all individual risk factors were significantly associated with WS and DA (with the exception of current smoking with DA in women and SFU with DA in both genders). Stronger dose-response relationships were seen in women for smoking amounts and duration; BMI showed stronger quadratic relationships. The combined risks were generally larger in women than in men, with significant risks for underweight (OR=2.73) as well as obese (OR=2.00) smokers for WS (OR=2.13 and OR=1.58 for DA, respectively). The magnitude of the combined effects from low/high BMI, smoking and drinking were also consistently higher among women than among men in WS and DA. SFU among underweight smokers also had positive association with WS (men and women) and DA (women).

conclusionsBMI, smoking, drinking and SFU-in combination-are associated with double or triple the risk of development of asthma. These risk factors might help explain the wide variation in asthma burden across countries.

Indexed as

AsthmaAsthma EpidemiologyTobacco and the lung

Identifiers

PMID27099758
PMCPMC4823466
OpenAlexW2338623460

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.