Evidence map›Paper›PMID 27099674›Full record

ArticleGastroenterology and hepatology from bed to bench2016

Autoimmune enteropathy: not all flat mucosa mean coeliac disease.

Umberto Volta, Maria Gloria Mumolo, Giacomo Caio, Elisa Boschetti, Rocco Latorre, Fiorella Giancola, Paola Paterini, Roberto De Giorgio

Open access · greenAbstract readCase Reports
In one paragraph

Article in Gastroenterology and hepatology from bed to bench, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Autoimmune enteropathies.Virchows Archiv : an international journal of pathology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Umberto VoltaDepartment of Medical and Surgical Sciences, University of Bologna, Italy.
Maria Gloria MumoloGastroenterology Unit, Department of Gastroenterology, University of Pisa, Italy.
Giacomo CaioDepartment of Medical and Surgical Sciences, University of Bologna, Italy.
Elisa BoschettiDepartment of Medical and Surgical Sciences, University of Bologna, Italy.
Rocco LatorreDepartment of Medical and Surgical Sciences, University of Bologna, Italy.
Fiorella GiancolaDepartment of Medical and Surgical Sciences, University of Bologna, Italy.
Paola PateriniDepartment of Medical and Surgical Sciences, University of Bologna, Italy.
Roberto De GiorgioDepartment of Medical and Surgical Sciences, University of Bologna, Italy.
University of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 62-year-old woman complaining of severe malabsorption was diagnosed with celiac disease based on the findings of flat, small intestinal mucosa and HLA-DQ2 positivity, although celiac serology was negative. This diagnosis was questioned due to the lack of clinical and histological improvement after a long period of strict gluten-free diet. The detection of enterocyte autoantibodies guided to the correct diagnosis of autoimmune enteropathy, leading to a complete recovery of the patient following an appropriate immunosuppressive treatment. Autoimmune enteropathy should be considered in the differential diagnosis of malabsorption with severe villous atrophy, including those cases with negative celiac-related serology.

Indexed as

Autoimmune enteropathyEnterocyte autoantibodiesMalabsorptionVillous atrophy

Identifiers

PMID27099674
PMCPMC4833853
OpenAlexW2303796801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.