Evidence map›Paper›PMID 27098922›Full record

ReviewDysphagia2016

Pathophysiology of Radiation-Induced Dysphagia in Head and Neck Cancer.

Suzanne N King, Neal E Dunlap, Paul A Tennant, Teresa Pitts

Open access · greenAbstract readReview
In one paragraph

Review in Dysphagia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 7 pooled it
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 7 syntheses or guidelines pooled it, 238 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Article
  16. Article
  17. Article
  18. Article
  19. Patients' experiences of dysphagia and rehabilitation care needs across the pre-, intra-, and post-radiotherapy phases for head and neck cancer: a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  20. Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Suzanne N KingDepartment of Neurological Surgery, Kentucky Spinal Cord Injury Research Center, University of Louisville, 511 South Floyd St MDR 616, Louisville, KY, 40202, USA.
Neal E DunlapDepartment of Radiation Oncology, University of Louisville, Louisville, USA.
Paul A TennantDepartment of Otolaryngology-Head and Neck Surgery and Communicative Disorders, University of Louisville, Louisville, USA.
Teresa PittsDepartment of Neurological Surgery, Kentucky Spinal Cord Injury Research Center, University of Louisville, 511 South Floyd St MDR 616, Louisville, KY, 40202, USA. t.pitts@louisville.edu.
University of Louisville · US

Funding

Regulation of Airway Protective BehaviorsR00HL111215 · NHLBI · UNIVERSITY OF LOUISVILLE · PI PITTS, TERESA G · 2015 to 2017
$731k
Regulation of Airway Protective BehaviorsK99HL111215 · NHLBI · UNIVERSITY OF FLORIDA · PI PITTS, TERESA G · 2013 to 2014
$267k
NHLBI NIH HHS K99 HL111215NHLBI NIH HHS R00 HL111215
6 · The paper itself

Abstract

Oncologic treatments, such as curative radiotherapy and chemoradiation, for head and neck cancer can cause long-term swallowing impairments (dysphagia) that negatively impact quality of life. Radiation-induced dysphagia comprised a broad spectrum of structural, mechanical, and neurologic deficits. An understanding of the biomolecular effects of radiation on the time course of wound healing and underlying morphological tissue responses that precede radiation damage will improve options available for dysphagia treatment. The goal of this review is to discuss the pathophysiology of radiation-induced injury and elucidate areas that need further exploration.

Indexed as

ChemoradiotherapyDeglutition DisordersHead and Neck NeoplasmsHumansRadiation InjuriesCancerDeglutitionDeglutition disordersFibrosisPharynxRadiationSwallow

Identifiers

PMID27098922
PMCPMC5340192
OpenAlexW2341627898

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.