Evidence map›Paper›PMID 27098498›Full record

ArticleXenobiotica; the fate of foreign compounds in biological systems2017

Disposition of the emerging brominated flame retardant, bis(2-ethylhexyl) tetrabromophthalate, in female Sprague Dawley rats: effects of dose, route and repeated administration.

Gabriel A Knudsen, J Michael Sanders, Linda S Birnbaum

Abstract read
In one paragraph

Article in Xenobiotica; the fate of foreign compounds in biological systems, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. A physiologically based pharmacokinetic model of diethyl phthalates in humans.Environmental pollution (Barking, Essex : 1987) · 2024
    Article
  5. Article
  6. Article
  7. 2,4,6-Tribromophenol Disposition and Kinetics in Pregnant and Nursing Sprague Dawley Rats.Toxicological sciences : an official journal of the Society of Toxicology · 2020
    Article
  8. 2,4,6-Tribromophenol Disposition and Kinetics in Rodents: Effects of Dose, Route, Sex, and Species.Toxicological sciences : an official journal of the Society of Toxicology · 2019
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. The biological fate of decabromodiphenyl ethane following oral, dermal or intravenous administration.Xenobiotica; the fate of foreign compounds in biological systems · 2017
    Article
  14. Article
  15. Editor's Highlight: Transplacental and Lactational Transfer of Firemaster® 550 Components in Dosed Wistar Rats.Toxicological sciences : an official journal of the Society of Toxicology · 2016
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gabriel A Knudsena NCI Laboratory of Toxicology and Toxicokinetics , NC , USA.
J Michael Sandersa NCI Laboratory of Toxicology and Toxicokinetics , NC , USA.
Linda S Birnbauma NCI Laboratory of Toxicology and Toxicokinetics , NC , USA.

Funding

Studies of the fate of environmental contaminants in humans and animalsZIABC011476 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BIRNBAUM, LINDA · 2013 to 2019
$5.8M
Intramural NIH HHS ZIA BC011476
6 · The paper itself

Abstract

1. Bis(2-ethylhexyl)-tetrabromophthalate (BEH-TEBP; CAS No. 26040-51-7; PubChem CID: 117291; MW 706.15 g/mol, elsewhere: TeBrDEPH, TBPH, or BEHTBP) is used as an additive brominated flame retardant in consumer products. 2. Female Sprague Dawley rats eliminated 92-98% of [

Indexed as

Administration, OralAnimalsBileDose-Response Relationship, DrugFemaleFlame RetardantsPhthalic AcidsRatsRats, Sprague-DawleyTissue DistributionToxicity Tests, Chronicbis(2-ethylhexyl)-2,3,4,5-tetrabromophtalateFlame RetardantsPhthalic AcidsADMEbioaccumulationbrominated flame retardantpersistent organic pollutantphthalate ester

Identifiers

PMID27098498
PMCPMC5531283
OpenAlexW2336129168

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.