Evidence map›Paper›PMID 27098413›Full record

ArticleJournal of the American Society for Mass Spectrometry2016

A Structures for Lossless Ion Manipulations (SLIM) Module for Collision Induced Dissociation.

Ian K Webb, Sandilya V B Garimella, Randolph V Norheim, Erin S Baker, Yehia M Ibrahim, Richard D Smith

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. The Potential for Ion Mobility in Pharmaceutical and Clinical Analyses.Advances in experimental medicine and biology · 2026
    Review
  2. Review
  3. Article
  4. Towards IMInternational journal of mass spectrometry · 2024
    Article
  5. SLIM Tricks: Tools, Concepts, and Strategies for the Development of Planar Ion Guides.Journal of the American Society for Mass Spectrometry · 2023
    Article
  6. Identification of Mobility-ResolvedAnalytical chemistry · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ian K WebbBiological Sciences Division and Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, 3335 Innovation Ave. (K8-98), P.O. Box 999, Richland, WA, 99352, USA.
Sandilya V B GarimellaBiological Sciences Division and Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, 3335 Innovation Ave. (K8-98), P.O. Box 999, Richland, WA, 99352, USA.
Randolph V NorheimBiological Sciences Division and Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, 3335 Innovation Ave. (K8-98), P.O. Box 999, Richland, WA, 99352, USA.
Erin S BakerBiological Sciences Division and Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, 3335 Innovation Ave. (K8-98), P.O. Box 999, Richland, WA, 99352, USA.
Yehia M IbrahimBiological Sciences Division and Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, 3335 Innovation Ave. (K8-98), P.O. Box 999, Richland, WA, 99352, USA.
Richard D SmithBiological Sciences Division and Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, 3335 Innovation Ave. (K8-98), P.O. Box 999, Richland, WA, 99352, USA. rds@pnnl.gov.
Environmental Molecular Sciences Laboratory · USPacific Northwest National Laboratory · US

Funding

Equipment Supplement Request for a Research Resource for Ultra-sensitive High Throughput ProteomicsP41GM103493 · NIGMS · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI SMITH, RICHARD D · 2012 to 2022
$22.6M
NIGMS NIH HHS P41 GM103493
6 · The paper itself

Abstract

A collision induced dissociation (CID) structure for lossless ion manipulations (SLIM) module is introduced and coupled to a quadrupole time-of-flight (QTOF) mass spectrometer. The SLIM CID module was mounted after an ion mobility (IM) drift tube to enable IM/CID/MS studies. The efficiency of CID was studied by using the model peptide leucine enkephalin. CID efficiencies (62%) compared favorably with other beam-type CID methods. Additionally, the SLIM CID module was used to fragment a mixture of nine peptides after IM separation. This work also represents the first application of SLIM in the 0.3 to 0.5 Torr pressure regime, an order of magnitude lower in pressure than previously studied. Graphical Abstract ᅟ.

Indexed as

Collision induced dissociationConveyorIon mobility spectrometryIon opticsManipulationPeptide fragmentationrf Confinement

Identifiers

PMID27098413
PMCPMC4899216
OpenAlexW2338758422

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.