ArticleInternational journal of cancer2016
Record linkage to correct under-ascertainment of cancers in HIV cohorts: The Sinikithemba HIV clinic linkage project.
Article in International journal of cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Paracrine signals from HIV-1-infected immune cells reprogram cervical cancer pathways.iScience · 2026Article
- Record linkage without patient identifiers: Proof of concept using data from South Africa's national HIV program.PLOS global public health · 2025Article
- State of the science and future directions for research on HIV and cancer: Summary of a joint workshop sponsored by IARC and NCI.International journal of cancer · 2024Review
- Gynaecologic and breast cancers in women living with HIV in South Africa: A record linkage study.International journal of cancer · 2024Article
- Diffuse Large B-Cell Lymphoma in the HIV Setting.Cancers · 2023Review
- Linking population-based cohorts with cancer registries in LMIC: a case study and lessons learnt in India.BMJ open · 2023Article
- Cancer incidence among people living with HIV in Zimbabwe: A record linkage study.Cancer reports (Hoboken, N.J.) · 2022Article
- Cohort profile: the South African HIV Cancer Match (SAM) Study, a national population-based cohort.BMJ open · 2022Article
- Epidemiology of haematological malignancies in people living with HIV.The lancet. HIV · 2020Review
- Cervical cancer risk in women living with HIV across four continents: A multicohort study.International journal of cancer · 2020Observational
- High Cancer Burden Among Antiretroviral Therapy Users in Malawi: A Record Linkage Study of Observational Human Immunodeficiency Virus Cohorts and Cancer Registry Data.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Observational
- Using national laboratory data to assess cumulative frequency of linkage after transfer to community-based HIV clinics in South Africa.Journal of the International AIDS Society · 2019Article
- Brief Report: Malignancies in Adults Living With HIV in Asia.Journal of acquired immune deficiency syndromes (1999) · 2019Article
- Probabilistic record linkage of de-identified research datasets with discrepancies using diagnosis codes.Scientific data · 2019Article
- Non-Hodgkin lymphoma risk in adults living with HIV across five continents.AIDS (London, England) · 2018Article
- Assessing the completeness and accuracy of South African National Laboratory CD4 and viral load data: a cross-sectional study.BMJ open · 2018Article
- Analysis of risk factors associated with hepatocellular carcinoma in black South Africans: 2000-2012.PloS one · 2018Article
- Comparison of Kaposi Sarcoma Risk in Human Immunodeficiency Virus-Positive Adults Across 5 Continents: A Multiregional Multicohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017Article
- Cervical cancer risk and impact of Pap-based screening in HIV-positive women on antiretroviral therapy in Johannesburg, South Africa.International journal of cancer · 2017Article
- Imputing HIV treatment start dates from routine laboratory data in South Africa: a validation study.BMC health services research · 2017Article
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8 authors.
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Abstract
The surveillance of HIV-related cancers in South Africa is hampered by the lack of systematic collection of cancer diagnoses in HIV cohorts and the absence of HIV status in cancer registries. To improve cancer ascertainment and estimate cancer incidence, we linked records of adults (aged ≥ 16 years) on antiretroviral treatment (ART) enrolled at Sinikithemba HIV clinic, McCord Hospital in KwaZulu-Natal (KZN) with the cancer records of public laboratories in KZN province using probabilistic record linkage (PRL) methods. We calculated incidence rates for all cancers, Kaposi sarcoma (KS), cervix, non-Hodgkin's lymphoma and non-AIDS defining cancers (NADCs) before and after inclusion of linkage-identified cancers with 95% confidence intervals (CIs). A total of 8,721 records of HIV-positive patients were linked with 35,536 cancer records. Between 2004 and 2010, we identified 448 cancers, 82% (n = 367) were recorded in the cancer registry only, 10% (n = 43) in the HIV cohort only and 8% (n = 38) both in the HIV cohort and the cancer registry. The overall cancer incidence rate in patients starting ART increased from 134 (95% CI 91-212) to 877 (95% CI 744-1,041) per 100,000 person-years after inclusion of linkage-identified cancers. Incidence rates were highest for KS (432, 95% CI 341-555), followed by cervix (259, 95% CI 179-390) and NADCs (294, 95% CI 223-395) per 100,000 person-years. Ascertainment of cancer in HIV cohorts is incomplete, PRL is both feasible and essential for cancer ascertainment.
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