ArticleAnnals of biomedical engineering2017
Hemodynamic Performance and Thrombogenic Properties of a Superhydrophobic Bileaflet Mechanical Heart Valve.
Article in Annals of biomedical engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 60 citations in OpenAlex.
- Silicon Nitride Coatings on Titanium for Cardiovascular Applications: Interface Engineering, Hemocompatibility, and Translational Challenges.Materials (Basel, Switzerland) · 2026Review
- Nanoparticle Biofunctionalization of Bioprosthetic Heart Valves to Modulate Mechanisms of Structural Valve Deterioration.JACC. Basic to translational science · 2026Article
- Impact of Vascular Geometry on Thrombosis in Pediatric Patients With Modified Blalock-Taussig-Thomas Shunt: A Pilot Study.Journal of the American Heart Association · 2025Article
- Cardiovascular patches applied in congenital cardiac surgery: Current materials and prospects.Bioengineering & translational medicine · 2025Review
- Thirty-year outcomes of low-intensity anticoagulation for mechanical aortic valve.Heart and vessels · 2024Article
- New insights and novel perspectives in bileaflet mechanical heart valve prostheses thromboresistance.Journal of cardiothoracic surgery · 2024Article
- Rethinking mechanical heart valves in the aortic position: new paradigms in design and testing.Frontiers in cardiovascular medicine · 2024Review
- Bio-inspired hemocompatible surface modifications for biomedical applications.Progress in materials science · 2022Article
- Surface modification strategies to improve titanium hemocompatibility: a comprehensive review.Materials advances · 2021Review
- Potential of Superhydrophobic Surface for Blood-Contacting Medical Devices.International journal of molecular sciences · 2021Review
- Laser Superficial Fusion of Gold Nanoparticles with PEEK Polymer for Cardiovascular Application.Materials (Basel, Switzerland) · 2021Article
- Clinical mid-term outcomes of the Chinese-made CL-V bileaflet mechanical heart valve in Chinese patients.Journal of thoracic disease · 2021Article
- Calcific Aortic Stenosis-A Review on Acquired Mechanisms of the Disease and Treatments.Frontiers in cardiovascular medicine · 2021Review
- Impact of superhydrophobicity on the fluid dynamics of a bileaflet mechanical heart valve.Journal of the mechanical behavior of biomedical materials · 2020Article
- Hemocompatibility of Super-Repellent surfaces: Current and Future.Materials horizons · 2019Article
- Adverse Hemodynamic Conditions Associated with Mechanical Heart Valve Leaflet Immobility.Bioengineering (Basel, Switzerland) · 2018Article
- Review of numerical methods for simulation of mechanical heart valves and the potential for blood clotting.Medical & biological engineering & computing · 2017Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
In this study, we explore how blood-material interactions and hemodynamics are impacted by rendering a clinical quality 25 mm St. Jude Medical Bileaflet mechanical heart valve (BMHV) superhydrophobic (SH) with the aim of reducing thrombo-embolic complications associated with BMHVs. Basic cell adhesion is evaluated to assess blood-material interactions, while hemodynamic performance is analyzed with and without the SH coating. Results show that a SH coating with a receding contact angle (CA) of 160° strikingly eliminates platelet and leukocyte adhesion to the surface. Alternatively, many platelets attach to and activate on pyrolytic carbon (receding CA = 47), the base material for BMHVs. We further show that the performance index increases by 2.5% for coated valve relative to an uncoated valve, with a maximum possible improved performance of 5%. Both valves exhibit instantaneous shear stress below 10 N/m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.