Evidence map›Paper›PMID 27098045›Full record

ReviewNPJ primary care respiratory medicine2016

Inhaler technique: facts and fantasies. A view from the Aerosol Drug Management Improvement Team (ADMIT).

Mark L Levy, P N R Dekhuijzen, P J Barnes, M Broeders, C J Corrigan, B L Chawes, L Corbetta, J C Dubus, Th Hausen, F Lavorini and 8 more

Erratum issuedAbstract readReview
In one paragraph

Review in NPJ primary care respiratory medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. WeChat Public Account Use Improves Clinical Control of Cough-Variant Asthma: A Randomized Controlled Trial.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Trial
  4. Trial
  5. Treatment of bronchial asthma - A simplified overview.Lung India : official organ of Indian Chest Society · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Perception of burden of oral and inhaled corticosteroid adverse effects on asthma-specific quality of life.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2023
    Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. The Role of the Pharmacist in Inhaler Selection and Education in Chronic Obstructive Pulmonary Disease.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2021
    Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Mark L LevyGeneral Practitioner and Respiratory Lead, Harrow, London, UK.ORCID http://orcid.org/0000-0002-1807-3246
P N R DekhuijzenRadboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
P J BarnesNational Heart and Lung Institute, Imperial College London, London, UK.
M BroedersUniversity Medical Centre Nijmegen, Nijmegen, The Netherlands.
C J CorriganDepartment of Respiratory Medicine and Allergy, King's College London School of Medicine, London, UK.
B L ChawesCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
L CorbettaDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
J C DubusUnité de Medicine Infantile, Marseille, France.
Th HausenEssen, Germany.
F LavoriniDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
N RocheService de Pneumologie et Soins Intensifs Respiratoires, Groupe Hospitalier Cochin, Université Paris-Descartes, Paris, France.
J SanchisDepartament de Pneumologia, Hospital de la Santa Creuide Sant Pau, Universitat Autónoma de Barcelona, Barcelona, Spain.
Omar S UsmaniNIHR Career Development Fellow, National Heart and Lung Institute (NHLI), Imperial College London, UK.
J ViejoHospital General Yagüe de Burgos, Spain.
W VinckenUniversitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Dienst Pneumologie, Brussels, Belgium.
Th VoshaarKrankenhaus Bethanien, Moers, Germany.
G K CromptonEdinburgh, UK.
Soren PedersenPediatric Research Unit, University of Southern Denmark, Kolding Hospital, Kolding, Denmark.

Funding

Medical Research Council G0200485Medical Research Council G1000758
6 · The paper itself

Abstract

Health professionals tasked with advising patients with asthma and chronic obstructive pulmonary disease (COPD) how to use inhaler devices properly and what to do about unwanted effects will be aware of a variety of commonly held precepts. The evidence for many of these is, however, lacking or old and therefore in need of re-examination. Few would disagree that facilitating and encouraging regular and proper use of inhaler devices for the treatment of asthma and COPD is critical for successful outcomes. It seems logical that the abandonment of unnecessary or ill-founded practices forms an integral part of this process: the use of inhalers is bewildering enough, particularly with regular introduction of new drugs, devices and ancillary equipment, without unnecessary and pointless adages. We review the evidence, or lack thereof, underlying ten items of inhaler 'lore' commonly passed on by health professionals to each other and thence to patients. The exercise is intended as a pragmatic, evidence-informed review by a group of clinicians with appropriate experience. It is not intended to be an exhaustive review of the literature; rather, we aim to stimulate debate, and to encourage researchers to challenge some of these ideas and to provide new, updated evidence on which to base relevant, meaningful advice in the future. The discussion on each item is followed by a formal, expert opinion by members of the ADMIT Working Group.

Indexed as

Administration, InhalationAerosolsAsthmaBronchodilator AgentsEquipment DesignHumansNebulizers and VaporizersPulmonary Disease, Chronic ObstructiveAerosolsBronchodilator Agents

Identifiers

PMID27098045
PMCPMC4839029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.