Evidence map›Paper›PMID 27097810›Full record

SynthesisVirchows Archiv : an international journal of pathology2016

The effects of implementing synoptic pathology reporting in cancer diagnosis: a systematic review.

Caro E Sluijter, Luc R C W van Lonkhuijzen, Henk-Jan van Slooten, Iris D Nagtegaal, Lucy I H Overbeek

Abstract readSystematic Review
In one paragraph

Synthesis in Virchows Archiv : an international journal of pathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. ISUOG/ESGO Consensus Statement on ultrasound-guided biopsy in gynecological oncology.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025
    Guideline
  3. From operating room to pathology report: Delphi consensus on pathological assessment of peritoneal cytology and biopsies in staging laparoscopy for gastric cancer.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Characterizing Interpretive and Diagnostic Competency Development in Pathology Training.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Caro E SluijterDepartment of Pathology, Radboud University Medical Centre, Huispost 824, P.O. Box 9101, 6500, HB, Nijmegen, The Netherlands. caro.e.sluijter@radboudumc.nl.
Luc R C W van LonkhuijzenCentre for Gynaecological Oncology, Academic Medical Centre, Amsterdam, The Netherlands.
Henk-Jan van SlootenFoundation PALGA (The Nationwide Network and Registry of Histo- and Cytopathology in the Netherlands), Houten, The Netherlands.
Iris D NagtegaalDepartment of Pathology, Radboud University Medical Centre, Huispost 824, P.O. Box 9101, 6500, HB, Nijmegen, The Netherlands.
Lucy I H OverbeekFoundation PALGA (The Nationwide Network and Registry of Histo- and Cytopathology in the Netherlands), Houten, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathology reporting is evolving from a traditional narrative report to a more structured synoptic report. Narrative reporting can cause misinterpretation due to lack of information and structure. In this systematic review, we evaluate the impact of synoptic reporting on completeness of pathology reports and quality of pathology evaluation for solid tumours. Pubmed, Embase and Cochrane databases were systematically searched to identify studies describing the effect of synoptic reporting implementation on completeness of reporting and quality of pathology evaluation of solid malignant tumours. Thirty-three studies met the inclusion criteria. All studies, except one, reported an increased overall completeness of pathology reports after introduction of synoptic reporting (SR). Most frequently studied cancers were breast (n = 9) and colorectal cancer (n = 16). For breast cancer, narrative reports adequately described 'tumour type' and 'nodal status'. Synoptic reporting resulted in improved description of 'resection margins', 'DCIS size', 'location' and 'presence of calcifications'. For colorectal cancer, narrative reports adequately reported 'tumour type', 'invasion depth', 'lymph node counts' and 'nodal status'. Synoptic reporting resulted in increased reporting of 'circumferential margin', 'resection margin', 'perineural invasion' and 'lymphovascular invasion'. In addition, increased numbers of reported lymph nodes were found in synoptic reports. Narrative reports of other cancer types described the traditional parameters adequately, whereas for 'resection margins' and '(lympho)vascular/perineural invasion', implementation of synoptic reporting was necessary. Synoptic reporting results in improved reporting of clinical relevant data. Demonstration of clinical impact of this improved method of pathology reporting is required for successful introduction and implementation in daily pathology practice.

Indexed as

Medical RecordsPathology, SurgicalPractice Guidelines as TopicBreast NeoplasmsColorectal NeoplasmsDatabases, FactualFemaleHumansBreast cancerChecklistColorectal carcinomaCompletenessGuidelineNarrative reportingPathologyProformaQualitySynoptic reportingTemplate

Identifiers

PMID27097810
PMCPMC4887530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.