Evidence map›Paper›PMID 27096714›Full record

ReviewHuman vaccines & immunotherapeutics2016

Surveillance of pneumococcal diseases in Central and Eastern Europe.

Mehmet Ceyhan, Ron Dagan, Abdullah Sayiner, Liudmyla Chernyshova, Ener Çağrı Dinleyici, Waleria Hryniewicz, Andrea Kulcsár, Lucia Mad'arová, Petr Pazdiora, Sergey Sidorenko and 3 more

Open access · hybridAbstract readReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  3. Trends in the incidence and burden of otitis media in children: a global analysis from 1990 to 2021.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 13 institutions in 11 countries.

Mehmet Ceyhana Department of Pediatric Infectious Diseases , School of Medicine, Hacettepe University , Ankara , Turkey.
Ron Daganb Pediatric Infectious Disease Unit, Ben-Gurion University of the Negev , Beer-Sheva , Israel.
Abdullah Sayinerc Department of Chest Diseases , Ege University Faculty of Medicine , Izmir , Turkey.
Liudmyla Chernyshovad Department of Pediatric Infectious Diseases and Immunology , National Medical Academy for Postgraduate Education , Kiev , Ukraine.
Ener Çağrı Dinleyicie Eskisehir Osmangazi University Faculty of Medicine , Eskisehir , Turkey.
Waleria Hryniewiczf National Medicines Institute, Division of Clinical Microbiology and Infection Prevention , Warsaw , Poland.
Andrea Kulcsárg Department of Infectology , Joint Hospital Saint László and Saint István , Budapest , Hungary.
Lucia Mad'arováh National Reference Centre for Pneumococcal and Haemophilus Diseases, Regional Authority of Public Health , Banská Bystrica , Slovak Republic.
Petr Pazdiorai Department of Epidemiology , Charles University Faculty Hospital , Pilsen , Czech Republic.
Sergey Sidorenkoj Research Institute of Children's Infection , St. Petersburg , Russia.
Anca Streinu-Cercelk Carol Davila University of Medicine and Pharmacy , Bucharest , Romania.
Arjana Tambić-Andraševićl Department of Clinical Microbiology , University Hospital for Infectious Diseases , Zagreb , Croatia.
Lyazzat Yeraliyevam Research Institute of Fundamental and Applied Medicine, Asfendiyarov Kazakh National Medical University , Almaty , Kazakhstan.
Ben-Gurion University of the Negev · ILCarol Davila University of Medicine and Pharmacy · ROCharles University · CZEge University · TREskişehir Osmangazi University · TRHacettepe University · TRKazakh National Medical University · KZNarodowy Instytut Leków · PLPublic Health Authority of the Slovak Republic · SKShupyk National Healthcare University of Ukraine · UAThe Turner Scientific Research Institute for Children's Orthopedics · RUUnified Szent István and Szent László Hospital · HUUniversity Hospital Centre Zagreb · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pneumococcal infection is a major cause of morbidity and mortality worldwide. The burden of disease associated with S. pneumoniae is largely preventable through routine vaccination. Pneumococcal conjugate vaccines (e.g. PCV7, PCV13) provide protection from invasive pneumococcal disease as well as non-invasive infection (pneumonia, acute otitis media), and decrease vaccine-type nasopharyngeal colonisation, thus reducing transmission to unvaccinated individuals. PCVs have also been shown to reduce the incidence of antibiotic-resistant pneumococcal disease. Surveillance for pneumococcal disease is important to understand local epidemiology, serotype distribution and antibiotic resistance rates. Surveillance systems also help to inform policy development, including vaccine recommendations, and monitor the impact of pneumococcal vaccination. National pneumococcal surveillance systems exist in a number of countries in Central and Eastern Europe (such as Croatia, Czech Republic, Hungary, Poland, Romania and Slovakia), and some have introduced PCVs (Czech Republic, Hungary, Kazakhstan, Russia, Slovakia and Turkey). Those countries without established programs (such as Kazakhstan, Russia and Ukraine) may be able to learn from the experiences of those with national surveillance systems. The serotype distributions and impact of PCV13 on pediatric pneumococcal diseases are relatively similar in different parts of the world, suggesting that approaches to vaccination used elsewhere are also likely to be effective in Central and Eastern Europe. This article briefly reviews the epidemiology of pneumococcal disease, presents the latest surveillance data from Central and Eastern Europe, and discusses any similarities and differences in these data as well the potential implications for vaccination policies in the region.

Indexed as

Epidemiological MonitoringEuropeHealth PolicyHumansImmunization ProgramsPneumococcal InfectionsPneumococcal Vaccines13-valent pneumococcal vaccinePneumococcal Vaccinesburdencentral EuropeEastern Europeepidemiologymortalitypneumococcal conjugate vaccinespneumococcal diseasessurveillancevaccination

Identifiers

PMID27096714
PMCPMC4994721
OpenAlexW2335946473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.