Evidence map›Paper›PMID 27096380›Full record

ArticleZebrafish2016

Standardized Welfare Terms for the Zebrafish Community.

Nicola Goodwin, Natasha A Karp, Samuel Blackledge, Bradley Clark, Rosemary Keeble, Ceri Kovacs, Katrina N Murray, Michael Price, Peter Thompson, James Bussell

Abstract read
In one paragraph

Article in Zebrafish, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nicola Goodwin1 Research Support Facility, Wellcome Trust Sanger Institute , Cambridge, United Kingdom .
Natasha A Karp3 Mouse Informatics Group, Wellcome Trust Sanger Institute , Cambridge, United Kingdom .
Samuel Blackledge1 Research Support Facility, Wellcome Trust Sanger Institute , Cambridge, United Kingdom .
Bradley Clark1 Research Support Facility, Wellcome Trust Sanger Institute , Cambridge, United Kingdom .
Rosemary Keeble2 Department of Medicine, Laboratory of Molecular Biology, Cambridge University , Cambridge, United Kingdom .
Ceri Kovacs1 Research Support Facility, Wellcome Trust Sanger Institute , Cambridge, United Kingdom .
Katrina N Murray4 Zebrafish International Resource Center , Pathology and Health Services, Eugene, Oregon.
Michael Price1 Research Support Facility, Wellcome Trust Sanger Institute , Cambridge, United Kingdom .
Peter Thompson1 Research Support Facility, Wellcome Trust Sanger Institute , Cambridge, United Kingdom .
James Bussell1 Research Support Facility, Wellcome Trust Sanger Institute , Cambridge, United Kingdom .

Funding

Zebrafish International Resource Center (ZIRC)P40OD011021 · OD · UNIVERSITY OF OREGON · PI Zoltan Marton Varga · 2012 to 2026
$36.0M
NIH HHS P40 OD011021Wellcome Trust
6 · The paper itself

Abstract

Managing the welfare of laboratory animals is critical to animal health, vital in the understanding of phenotypes created by treatment or genetic alteration and ensures compliance of regulations. Part of an animal welfare assessment is the requirement to record observations, ensuring all those responsible for the animals are aware of their health status and can act accordingly. Although the use of zebrafish in research continues to increase, guidelines for conducting welfare assessments and the reporting of observations are considered unclear compared to mammalian species. To support the movement of zebrafish between facilities, significant improvement would be achieved through the use of standardized terms to ensure clarity and consistency between facilities. Improving the clarity of terminology around welfare not only addresses our ethical obligation but also supports the research goals and provides a searchable description of the phenotypes. A Collaboration between the Wellcome Trust Sanger Institute and Cambridge University (Department of Medicine-Laboratory of Molecular Biology) has led to the creation of the zebrafish welfare terms from which standardization of terminology can be achieved.

Indexed as

Terminology as TopicZebrafishAnimalsAnimal Welfare

Identifiers

PMID27096380
PMCPMC4931771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.