Evidence map›Paper›PMID 27095919›Full record

ArticleCentral-European journal of immunology2016

A natural herbal remedy modulates angiogenic activity of bronchoalveolar lavage cells from sarcoidosis patients.

Dorota M Radomska-Leśniewska, Ewa Skopińska-Różewska, Urszula Demkow, Jarosław Jóźwiak, Małgorzata Sobiecka, Barbara Joanna Bałan

Abstract read
In one paragraph

Article in Central-European journal of immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. The Fight against Infection and Pain: Devil's Claw (Molecules (Basel, Switzerland) · 2022
    Review
  3. Review
  4. Angiogenesis modulation by exogenous antioxidants.Central-European journal of immunology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dorota M Radomska-LeśniewskaDepartment of Histology and Embryology, Biostructure Centre, Medical University of Warsaw, Warsaw, Poland.
Ewa Skopińska-RóżewskaDepartment of Pathomorphology, Biostructure Centre, Medical University of Warsaw, Warsaw, Poland; Military Institute of Hygiene and Epidemiology, Warsaw, Poland.
Urszula DemkowDepartment of Laboratory Diagnostics and Clinical Immunology of Developmental Age, Medical University of Warsaw, Warsaw, Poland.
Jarosław JóźwiakDepartment of Histology and Embryology, Biostructure Centre, Medical University of Warsaw, Warsaw, Poland.
Małgorzata SobieckaI Department of Lung Diseases, National Institute of Tuberculosis and Lung Diseases, Warsaw, Poland.
Barbara Joanna BałanDepartment of Immunology, Biochemistry, and Nutrition, Medical University of Warsaw, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcoidosis is a systemic inflammatory disease with abnormally high angiogenic activity of inflammatory cells. Reumaherb preparation consisting of three herbs: Echinacea purpurea, Harpagophytum procumbens, and Filipendula ulmaria, and it exerts anti-inflammatory, antioxidant, and analgesic activity and stimulates regenerative and immunological processes. The aim of this paper was to estimate the effect of Reumaherb on immunological angiogenesis induced by bronchoalveolar lavage (BAL) cells collected from six patients with sarcoidosis and grafted into Balb/c mice skin. After grafting, the animals were fed for three days with 0.6 or 1.2 mg of Reumaherb (calculated from recommended human daily dose) daily, suspended in 40 µl of water, or 40 µl of water alone (control group). A significant reduction of newly formed blood vessels was obtained in four cases for 1.2 mg and in three cases for 0.6 mg daily dose of this remedy. Thus, we hypothesise that Reumaherb promotes anti-angiogenic activity and may potentially be used in diseases associated with excessive blood vessel formation.

Indexed as

BALbronchoalveolar lavage cellsherbal remedyleukocyte-induced angiogenesisLIAmurine skinsarcoidosis

Identifiers

PMID27095919
PMCPMC4829814

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.