ArticleJournal of microbiology (Seoul, Korea)2016
Photosynthetic inhibition and oxidative stress to the toxic Phaeocystis globosa caused by a diketopiperazine isolated from products of algicidal bacterium metabolism.
Article in Journal of microbiology (Seoul, Korea), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 55 citations in OpenAlex.
- Article
- Algicidal Effects of a High-Efficiency Algicidal BacteriumMarine drugs · 2022Article
- A Novel Algicidal Bacterium,Microbiology spectrum · 2022Article
- Algicidal Bacteria: A Review of Current Knowledge and Applications to Control Harmful Algal Blooms.Frontiers in microbiology · 2022Review
- Bacteria Associated WithFrontiers in microbiology · 2022Article
- Altering the Sex Pheromone Cyclo(l-Pro-l-Pro) of the DiatomInternational journal of molecular sciences · 2021Article
- The complete genome sequence of the algicidal bacteriumBiotechnology reports (Amsterdam, Netherlands) · 2020Article
- The Antialgal Mechanism of Luteolin-7-O-Glucuronide onInternational journal of environmental research and public health · 2019Article
- Growth Inhibition of Phaeocystis Globosa Induced by Luteolin-7-O-glucuronide from Seagrass Enhalus acoroides.International journal of environmental research and public health · 2019Article
- Effects of Lanthanum on the Photosystem II Energy Fluxes and Antioxidant System ofInternational journal of environmental research and public health · 2019Article
- Investigation of the Inhibitory Effects of Mangrove Leaves and Analysis of Their Active Components on Phaeocystis globosa during Different Stages of Leaf Age.International journal of environmental research and public health · 2018Article
- Combined algicidal effect of urocanic acid,RSC advances · 2018Article
- Trade-off between reproduction and lifespan of the rotifer Brachionus plicatilis under different food conditions.Scientific reports · 2017Article
- NprR-NprX Quorum-Sensing System Regulates the Algicidal Activity ofFrontiers in microbiology · 2017Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Algicidal bacteria have been turned out to be available for inhibiting Phaeocystis globosa which frequently caused harmful algal blooms and threatened to economic development and ecological balance. A marine bacterium Bacillus sp. Ts-12 exhibited significant algicidal activity against P. globosa by indirect attack. In present study, an algicidal compound was isolated by silica gel column, Sephadex G-15 column and HPLC, further identified as hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, cyclo-(Pro-Gly), by GC-MS and (1)H-NMR. Cyclo-(Pro-Gly) significantly increased the level of reactive oxygen species (ROS) within P. globosa cells, further activating the enzymatic and non-enzymatic antioxidant systems, including superoxide dismutase (SOD), catalase (CAT), glutathione (GSH) and ascorbic acid (AsA). The increase in methane dicarboxylic aldehyde (MDA) content showed that the surplus ROS induced lipid peroxidation on membrane system. Transmission electron microscope (TEM) and flow cytometry (FCM) analysis revealed that cyclo-(Pro-Gly) caused reduction of Chl-a content, destruction of cell membrane integrity, chloroplasts and nuclear structure. Real-time PCR assay showed that the transcriptions of photosynthesis related genes (psbA, psbD, rbcL) were significantly inhibited. This study indicated that cyclo-(Pro-Gly) from marine Bacillus sp. Ts-12 exerted photosynthetic inhibition and oxidative stress to P. globosa and eventually led to the algal cells lysis. This algicidal compound might be potential bio-agent for controlling P. globosa red tide.
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Registered trials
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