ArticleBMC psychiatry2016
Neurocognitive profile in major depressive disorders: relationship to symptom level and subjective memory complaints.
Article in BMC psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic Review and Meta-Analysis of the Association Between Subjective and Objective Cognitive Function in Mood Disorders.Bipolar disorders · 2026Pooled it
- Working memory associated with anti-suicidal ideation effect of repeated-dose intravenous ketamine in depressed patients.European archives of psychiatry and clinical neuroscience · 2021Trial
- Sex differences in subjective cognitive impairment among Chinese patients with depression: A large-scale cross-sectional study.General psychiatry · 2026Article
- A Secondary Analysis of Longitudinal Pilot-Study Data Investigating the Associations Between Health-Related Quality of Life and Executive Functions in Remitted Major Depressive Disorder and Developments Two-Years Following Cognitive Training.Scandinavian journal of psychology · 2026Article
- Evaluation of Short Term and Long Term Subjective and Objective Cognitive Outcomes Following ECT for Depression in a Naturalistic Ambulatory Setting: A Cohort Study.Alpha psychiatry · 2026Article
- Memory Function, Weight Loss, and Eating Disorder Psychopathology in Bariatric Surgery Patients: A 5-Year Follow-Up Study.Obesity facts · 2026Article
- Exploring the interrelationships among physical exercise, visuospatial working memory, and depression symptoms in university students.Scientific reports · 2025Article
- Aberrant resting-state functional network centrality and cognitive impairment in unmedicated, euthymic bipolar patients.BMC psychiatry · 2024Article
- Improvement of persistent impairments in executive functions and attention following electroconvulsive therapy in a case control longitudinal follow up study.BMC psychiatry · 2024Observational
- Perceived cognitive loss, symptomology, and psychological well-being with bipolar disorder.International journal of bipolar disorders · 2024Article
- Neurocognitive Characteristics of Patients Who Visited a Psychiatric Outpatient Clinic Requesting Treatment for Adult Attention-Deficit/Hyperactivity Disorder.Psychiatry investigation · 2024Article
- Peak width of skeletonized mean diffusivity as a neuroimaging biomarker in first-episode schizophrenia.Frontiers in neuroscience · 2024Article
- Mask wearing during neuropsychological assessment negatively impacts performance on verbal tests in older patients.Psychological assessment · 2023Article
- Short-term cognitive effects of repeated-dose esketamine in adolescents with major depressive disorder and suicidal ideation: a randomized controlled trial.Child and adolescent psychiatry and mental health · 2023Article
- Hippocampal subfield volumes in treatment resistant depression and serial ketamine treatment.Frontiers in psychiatry · 2023Article
- Electroconvulsive therapy triggers a reversible decrease in brain N-acetylaspartate.Frontiers in psychiatry · 2023Article
- Post-COVID-19 Syndrome is Rarely Associated with Damage of the Nervous System: Findings from a Prospective Observational Cohort Study in 171 Patients.Neurology and therapy · 2022Article
- Pharmacological targeting of cognitive impairment in depression: recent developments and challenges in human clinical research.Translational psychiatry · 2022Review
- Building a neurocognitive profile of suicidal risk in severe mental disorders.BMC psychiatry · 2022Article
- Cognitive Considerations in Major Depression: Evaluating the Effects of Pharmacotherapy and ECT on Mood and Executive Control Deficits.Brain sciences · 2022Article
Corrections and comments
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2 authors.
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Abstract
backgroundThe MATRICS Consensus Cognitive Battery (MCCB) was developed for schizophrenia patients, but is also being used to assess neurocognitive function in bipolar disorder. This study aims to describe neurocognitive differences in major depressive disorder patients and healthy controls with the MCCB, and to describe the relationship between depression symptom severity, subjective cognitive complaints, and objective cognitive test performance.
methodsThirty-three patients with major depressive disorder and 33 pairwise matched healthy controls were assessed with the MCCB. The patients were also assessed with the Montgomery-Åsberg Depression Rating Scale (MADRS) and the Everyday Memory Questionnaire (EMQ).
resultsOn all neurocognitive domains, the depression patients scored significantly lower than the controls. The level of impairment ranged from 21.0% (Working Memory) to 58.0% (Speed of Processing). There were significant associations between neurocognitive test performance and depression symptom severity, but not with subjective cognitive complaints.
conclusionsThe MCCB was applicable in this study of major depressive disorder, and revealed significant neurocognitive dysfunction in this group. At least one fifth of the patients were impaired on all cognitive domains, with Speed of Processing and Reasoning/Problem Solving being most strongly affected. The objective test scores were significantly related to depression severity, but not to subjective cognitive complaints.
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