Evidence map›Paper›PMID 27094260›Full record

ArticleParasitology2017

Insights on adaptive and innate immunity in canine leishmaniosis.

Shazia Hosein, Damer P Blake, Laia Solano-Gallego

Open access · hybridAbstract read
In one paragraph

Article in Parasitology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Hematological Ratios inAnimals : an open access journal from MDPI · 2026
    Article
  8. Pathogens (Basel, Switzerland) · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. StandardizedVeterinary sciences · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Q3 lab-on-chip real-time PCR for the diagnosis ofJournal of clinical microbiology · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Subcutaneous, Oral, and Intranasal Immunization of BALB/c Mice withTropical medicine and infectious disease · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Shazia HoseinDepartment of Pathology and Pathogen Biology,Royal Veterinary College,University of London,Hawkshead Lane,North Mymms,AL9 7TA,UK.
Damer P BlakeDepartment of Pathology and Pathogen Biology,Royal Veterinary College,University of London,Hawkshead Lane,North Mymms,AL9 7TA,UK.
Laia Solano-GallegoDepartment de Medicina i Cirurgia Animals,Facultat de Veterinària,Universitat Autònoma de Barcelona,08193 Cerdanyola del Valles,Barcelona,Spain.
University of London · GBUniversitat Autònoma de Barcelona · ES

Funding

Biotechnology and Biological Sciences Research Council BB/F016891/1
6 · The paper itself

Abstract

Canine leishmaniosis (CanL) is caused by the parasite Leishmania infantum and is a systemic disease, which can present with variable clinical signs, and clinicopathological abnormalities. Clinical manifestations can range from subclinical infection to very severe systemic disease. Leishmaniosis is categorized as a neglected tropical disease and the complex immune responses associated with Leishmania species makes therapeutic treatments and vaccine development challenging for both dogs and humans. In this review, we summarize innate and adaptive immune responses associated with L. infantum infection in dogs, and we discuss the problems associated with the disease as well as potential solutions and the future direction of required research to help control the parasite.

Indexed as

Adaptive ImmunityImmunity, InnateAnimalsCytokinesDisease ManagementDog DiseasesDogsHumansLeishmania infantumLeishmaniasisLeishmaniasis, VisceralNeglected DiseasesT-LymphocytesToll-Like ReceptorsVaccinationCytokinesToll-Like ReceptorsCanine leishmaniosiscytokine profilesimmunologyT-cell mediated immunitytoll-like receptors

Identifiers

PMID27094260
PMCPMC5264656
OpenAlexW2341386298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.