ArticleBMC cardiovascular disorders2016
Peripheral artery disease and exertional leg symptoms in diabetes patients in Ghana.
Article in BMC cardiovascular disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Burden of peripheral artery disease and risk factors among patients with diabetes mellitus in sub-Saharan Africa: a systematic review and meta-analysis.BMC endocrine disorders · 2025Pooled it
- Exploring the prevalence and risk factors of peripheral artery disease in patients with type 2 diabetes in sub-Saharan Africa: a systematic review and meta-analysis.Frontiers in clinical diabetes and healthcare · 2025Pooled it
- Correlates and predictors of peripheral artery disease in patients with type 2 diabetes mellitus in Calabar, Nigeria: a multicentre cross-sectional comparative study.Journal of diabetes and metabolic disorders · 2025Article
- Peripheral artery disease In West Africans with diabetes: a risk factor profile analysis.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- The correlation between muscle loss and the severity of vascular stenosis in elderly patients with peripheral artery disease: a retrospective analysis utilizing computed tomography.Aging clinical and experimental research · 2025Article
- The value of growth differentiation factor 15 as a biomarker for peripheral artery disease in diabetes patients.Diabetology & metabolic syndrome · 2025Article
- Prevalence of and Risk Factors for Peripheral Artery Disease in Rural South Africa: A Cross-Sectional Analysis of the HAALSI Cohort.Journal of the American Heart Association · 2024Article
- Prevalence and risk factors of lower extremity disease in high risk groups in Malawi: a stratified cross-sectional study.BMJ open · 2022Article
- Expectation and Satisfaction with Nursing Care among Hypertensives Receiving Care at a Resource-Constrained Hospital in Ghana.Nursing research and practice · 2020Article
- Arterial Stiffness Is Associated with Peripheral Sensory Neuropathy in Diabetes Patients in Ghana.Journal of diabetes research · 2018Article
- Metabolic syndrome and parental history of cardiovascular disease in young adults in urban Ghana.BMC public health · 2017Article
- Circulating Angiogenic Growth Factors in Diabetes Patients with Peripheral Arterial Disease and Exertional Leg Pain in Ghana.International journal of vascular medicine · 2017Article
- Arterial stiffness in hypertensive and type 2 diabetes patients in Ghana: comparison of the cardio-ankle vascular index and central aortic techniques.BMC endocrine disorders · 2016Article
- Peripheral sensory neuropathy in type 2 diabetes patients: A case control study in Accra, Ghana.Journal of clinical & translational endocrinology · 2016Article
- Circulating angiogenic factors in diabetes patients in a tertiary hospital in Ghana.Journal of diabetes and metabolic disorders · 2016Article
- Arterial Stiffness in Nonhypertensive Type 2 Diabetes Patients in Ghana.International journal of endocrinology · 2016Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPeripheral arterial disease (PAD) is a major health problem in diabetes patients in high-income countries, but the PAD burden in sub-Saharan Africa is largely undetermined. We studied the prevalence of PAD and exertional leg symptoms in diabetes (DM) patients in a tertiary hospital in Ghana.
methodsIn a case control study design, 485 DM and 330 non-diabetes participants were recruited. PAD was diagnosed as Ankle Brachial Index (ABI) < 0.9. Edinburgh Claudication Questionnaire (ECQ) was used to assess exertional leg symptoms.
resultsThe overall prevalence of classical intermittent claudication was 10.3 % and ABI-diagnosed PAD was 26.7 %, with 3.5 % of the participants having both classic intermittent claudication and ABI-diagnosed PAD. The prevalence of exertional leg symptoms were similar in diabetes patients with and without PAD. In non-diabetes participants, intermittent claudication and rest pain were higher in PAD patients than in non-PAD participants. In multivariable logistic regression, intermittent claudication [OR (95 % CI), 3.39 (1.14 - 8.1), p < 0.05] and rest pain [4.3 (1.58 - 9.67), p < 0.001] were independently associated with PAD in non-diabetes group, and rest pain [1.71 (1.13 - 2.17), p < 0.05] was associated with PAD in all participants.
conclusionsThere is high burden of PAD and exertional leg pains in DM patients in Ghana. PAD is expressed as intermittent claudication and rest pain in non-diabetes individuals.
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