Evidence map›Paper›PMID 27093312›Full record

ArticleIEEE transactions on bio-medical engineering2016

Noninvasive Imaging of High-Frequency Drivers and Reconstruction of Global Dominant Frequency Maps in Patients With Paroxysmal and Persistent Atrial Fibrillation.

Zhaoye Zhou, Qi Jin, Lin Yee Chen, Long Yu, Liqun Wu, Bin He

Abstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Persistent atrial fibrillation ablation: glimpsing the light ahead?Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. [Rhythm analysis of body surface potential mapping recordings from atrial fibrillation patients based on autocorrelation function].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2018
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhaoye Zhou
Qi Jin
Lin Yee Chen
Long Yu
Liqun Wu
Bin He

Funding

Three Dimensional Electrocardiographic ImagingR01HL080093 · NHLBI · UNIVERSITY OF MINNESOTA · PI HE, BIN · 2007 to 2010
$1.5M
NHLBI NIH HHS R01 HL080093
6 · The paper itself

Abstract

objectiveHighest dominant-frequency (DF) drivers maintaining atrial fibrillation (AF) activities are effective ablation targets for restoring sinus rhythms in patients. This study aims to investigate whether AF drivers with highest activation rate can be noninvasively localized by means of a frequency-based cardiac electrical imaging (CEI) technique, which may aid in the planning of ablation strategy and the investigation of the underlying mechanisms of AF.

methodA total of seven out of 13 patients were recorded with spontaneous paroxysmal or persistent AF and analyzed. The biatrial DF maps were reconstructed by coupling 5-s BSPM with CT-determined patient geometry. The CEI results were compared with ablation sites and DFs found from BSPMs.

resultsCEI imaged left-to-right maximal frequency gradient (7.42 ± 0.66 Hz versus 5.85 ± 1.2 Hz, LA versus RA, p < 0.05) in paroxysmal AF patients. Patients with persistent AF were imaged with a loss of the intrachamber frequency gradient and a dispersion of the fast sources in both chambers. CEI was able to capture the AF behaviors, which were characterized by short-term stability, dynamic transition, and spatial repetition of the highest DF sites. The imaged highest DF sites were consistent with ablation sites in patients studied.

conclusionsThe frequency-based CEI allows localization of AF drivers with highest DF and characterization of the spatiotemporal frequency behaviors, suggesting the possibility for individualizing treatment strategy and advancing understanding of the underlying AF mechanisms. SIGNIFICANCE: The establishment of noninvasive imaging techniques localizing AF drivers would facilitate management of this significant cardiac arrhythmia.

Indexed as

AdultAgedAtrial FibrillationBody Surface Potential MappingCardiac Imaging TechniquesFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedSignal Processing, Computer-AssistedTomography, X-Ray Computed

Identifiers

PMID27093312
PMCPMC5063686

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.