Evidence map›Paper›PMID 27093238›Full record

ArticleCulture, health & sexuality2016

When and why women might suspend PrEP use according to perceived seasons of risk: implications for PrEP-specific risk-reduction counselling.

Emily Namey, Kawango Agot, Khatija Ahmed, Jacob Odhiambo, Joseph Skhosana, Greg Guest, Amy Corneli

Abstract read
In one paragraph

Article in Culture, health & sexuality, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  18. Multilevel Factors Influencing Interruptions in PrEP Use Among Young Women in Siaya County, Kenya.AIDS education and prevention : official publication of the International Society for AIDS Education · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emily Nameya Department of Social and Behavioral Health Sciences , FHI 360 , Durham , USA.
Kawango Agotb Impact Research and Development Organization , Kisumu , Kenya.
Khatija Ahmedc Setshaba Research Centre , Soshanguve , South Africa.
Jacob Odhiambob Impact Research and Development Organization , Kisumu , Kenya.
Joseph Skhosanac Setshaba Research Centre , Soshanguve , South Africa.
Greg Guesta Department of Social and Behavioral Health Sciences , FHI 360 , Durham , USA.
Amy Cornelia Department of Social and Behavioral Health Sciences , FHI 360 , Durham , USA.

Funding

PrEP and Risk Compensation: Assessing Effect and Preparing for RolloutR01MH095531 · NIMH · FAMILY HEALTH INTERNATIONAL · PI CORNELI, AMY LYNN · 2011 to 2013
$1.1M
NIMH NIH HHS R01 MH095531
6 · The paper itself

Abstract

Oral pre-exposure prophylaxis (PrEP) using the antiretroviral drug emtricitabine/tenofovir disoproxil fumarate (Truvada) has been shown to dramatically reduce the risk of HIV acquisition for women at higher risk of infection if taken daily. Understanding when and why women would intentionally stop using an efficacious oral PrEP drug within the context of their 'normal' daily lives is essential for delivering effective PrEP risk-reduction counselling. As part of a larger study, we conducted 60 qualitative interviews with women at higher risk of HIV in Bondo, Kenya, and Pretoria, South Africa. Participants charted their sexual contacts over the previous six months, indicated whether they would have taken PrEP if available and discussed whether and why they would have suspended PrEP use. Nearly all participants said they would have used PrEP in the previous six months; half indicated they would have suspended PrEP use at some point. Participants' reasons for an extended break from PrEP were related to partnership dynamics (e.g., perceived low risk of a stable partner) and phases of life (e.g., trying to conceive). Life events (e.g., holidays and travel) could prompt shorter breaks in PrEP use. These circumstances may or may not correspond to actual contexts of lower risk, highlighting the importance of tailored PrEP risk-reduction counselling.

Indexed as

Medication AdherenceAdultAnti-HIV AgentsFemaleHIV InfectionsHumansKenyaPre-Exposure ProphylaxisQualitative ResearchRisk Reduction BehaviorSafe SexSexual BehaviorSexual PartnersSouth AfricaTravelAnti-HIV AgentsHIV preventionKenyapre-exposure prophylaxisPrEP counsellingSouth Africawomen

Identifiers

PMID27093238
PMCPMC5049692

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.