ArticleNature immunology2016
Parallels and differences between innate and adaptive lymphocytes.
Article in Nature immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- From Glycocalyx Shedding to Microvascular Collapse in Sepsis: Endothelial Pathophysiology, Organ Dysfunction, and Mechanistic Biomarkers.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026Review
- Compensatory mechanisms in γδ T cell-deficient chickens followingFrontiers in immunology · 2025Article
- Renal IL-23-Dependent Type 3 Innate Lymphoid Cells Link Crystal-induced Intrarenal Inflammasome Activation with Kidney Fibrosis.Journal of immunology (Baltimore, Md. : 1950) · 2024Article
- The gene regulatory basis of bystander activation in CD8Science immunology · 2024Article
- Article
- Dynamic surveillance of lymphocyte subsets in patients with non-small cell lung cancer during chemotherapy or combination immunotherapy for early prediction of efficacy.Frontiers in immunology · 2024Article
- Chicken γδ T cells proliferate upon IL-2 and IL-12 treatment and show a restricted receptor repertoire in cell culture.Frontiers in immunology · 2024Article
- Shaping immunity for life: Layered development of CD8Immunological reviews · 2023Review
- Review
- Overview: Themes in Innate Lymphoid Cell Biology.Advances in experimental medicine and biology · 2022Article
- Probiotics and Trained Immunity.Biomolecules · 2021Review
- CTLA-4 in Regulatory T Cells for Cancer Immunotherapy.Cancers · 2021Review
- Mechanisms of activation of innate-like intraepithelial T lymphocytes.Mucosal immunology · 2020Review
- Neonatal T Cells: A Reinterpretation.Annual review of immunology · 2020Review
- Decoding communication patterns of the innate immune system by quantitative proteomics.Journal of leukocyte biology · 2019Review
- Lineage Differentiation Program of Invariant Natural Killer T Cells.Immune network · 2017Review
- The checkpoint for agonist selection precedes conventional selection in human thymus.Science immunology · 2017Article
- Is adaptive-innate lymphocyte cross-talk driving mucosal disease?Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Cellular Innate Immunity: An Old Game with New Players.Journal of innate immunity · 2017Review
- Immune modules shared by innate lymphoid cells and T cells.The Journal of allergy and clinical immunology · 2016Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lymphocytes are essential in innate and adaptive immunity. Recent insights suggest that some innate lymphocytes execute functions with adaptive characteristics, while adaptive lymphocytes can operate in ways reminiscent of innate cells. Rather than partitioning lymphocytes according to the type of effector function they execute, we propose that a relevant discrimination relates to the existence of conventional T cells in a naive state. The naive state can be seen as an actively repressed condition that supports T cell diversity and enables the flexible differentiation of effector cells in a manner that best addresses the antigenic challenge. We discuss these considerations in the context of the relative roles of innate lymphoid cells and antigen-experienced T cells in the immune system.
Indexed as
Identifiers
27092806What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.