ReviewFrontiers in neurology2016
Nutrition and Vascular Supply of Retinal Ganglion Cells during Human Development.
Review in Frontiers in neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 24 citations in OpenAlex.
- Visual Field Changes in Diabetic Retinopathy: Natural History and after Pan-Retinal Photocoagulation in the Diabetic Retinopathy Study and the ETDRS.Ophthalmology. Retina · 2025Trial
- Vulnerable parafoveal microcirculation quadrant in patients with type 2 diabetes mellitus.Scientific reports · 2025Observational
- Influence of Carotid Artery Stenting on the Retina and Choroid.Translational vision science & technology · 2024Article
- The mitochondrial protein TIMM44 is required for angiogenesis in vitro and in vivo.Cell death & disease · 2023Article
- Association of macular structure, function, and vessel density with foveal threshold in advanced glaucoma.Scientific reports · 2022Article
- Frequency Doubling Technology Visual Field Loss in Fabry Subjects Related to Retinal Ganglion Cell Function as Explored by ERG and OSOME.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- Article
- Impact of Axial Eye Size on Retinal Microvasculature Density in the Macular Region.Journal of clinical medicine · 2020Article
- The Horizontal Raphe of the Human Retina and its Watershed Zones.Vision (Basel, Switzerland) · 2019Review
- Macular vessel density in untreated normal tension glaucoma with a hemifield defect.Japanese journal of ophthalmology · 2019Article
- Review
- Outer Retinal Layers' Thickness Changes in relation to Age and Choroidal Thickness in Normal Eyes.Journal of ophthalmology · 2019Article
- Novel Classification of Early-stage Systemic Hypertensive Changes in Human Retina Based on OCTA Measurement of Choriocapillaris.Scientific reports · 2018Article
- Parafoveal Nonperfusion Analysis in Diabetic Retinopathy Using Optical Coherence Tomography Angiography.Translational vision science & technology · 2018Article
- Optical Coherence Tomography Angiography Macular Vascular Density Measurements and the Central 10-2 Visual Field in Glaucoma.Journal of glaucoma · 2018Article
- The peripheral and Central Humphrey visual field - morphological changes during aging.BMC ophthalmology · 2017Observational
- Retinal Vascular Abnormalities in Different Types of Inherited Retinal Dystrophies Assessed by Optical Coherence Tomography Angiography.Journal of current ophthalmologyArticle
- Choroidal Thickness in Different Types of Inherited Retinal Dystrophies.Journal of ophthalmic & vision researchReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo review the roles of the different vascular beds nourishing the inner retina [retinal ganglion cells (RGCs)] during normal development of the human eye, using our own tissue specimens to support our conclusions.
methodsAn extensive search of the appropriate literature included PubMed, Google scholar, and numerous available textbooks. In addition, choroidal and retinal NADPH-diaphorase stained whole mount preparations were investigated.
resultsThe first critical interaction between vascular bed and RGC formation occurs in the sixth to eighth month of gestation leading to a massive reduction of RGCs mainly in the peripheral retina. The first 3 years of age are characterized by an intense growth of the eyeball to near adult size. In the adult eye, the influence of the choroid on inner retinal nutrition was determined by examining the peripheral retinal watershed zones in more detail.
conclusionThis delicately balanced situation of RGC nutrition is described in the different regions of the eye, and a new graphic presentation is introduced to combine morphological measurements and clinical visual field data.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.