ReviewFrontiers in systems neuroscience2016
Making Waves in the Brain: What Are Oscillations, and Why Modulating Them Makes Sense for Brain Injury.
Review in Frontiers in systems neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 42 citations in OpenAlex.
- Article
- Review
- Neurophysiological Markers of Reward Processing Can Inform Preclinical Neurorehabilitation Approaches for Cognitive Impairments Following Brain Injury.Brain sciences · 2025Review
- Imaging the large-scale and cellular response to focal traumatic brain injury in mouse neocortex.Experimental physiology · 2025Article
- What can neurofeedback and transcranial alternating current stimulation reveal about cross-frequency coupling?Frontiers in neuroscience · 2025Article
- Imaging the large-scale and cellular response to focal traumatic brain injury in mouse neocortex.bioRxiv : the preprint server for biology · 2024Article
- Bumetanide induces post-traumatic microglia-interneuron contact to promote neurogenesis and recovery.Brain : a journal of neurology · 2023Article
- Brain rhythms control microglial response and cytokine expression via NF-κB signaling.Science advances · 2023Article
- Neuroprosthetics: from sensorimotor to cognitive disorders.Communications biology · 2023Review
- Orientation selective DBS of entorhinal cortex and medial septal nucleus modulates activity of rat brain areas involved in memory and cognition.Scientific reports · 2022Article
- The influential factors and non-pharmacological interventions of cognitive impairment in children with ischemic stroke.Frontiers in neurology · 2022Review
- Right Anterior Theta Hypersynchrony as a Quantitative Measure Associated with Autistic Traits and K-Cl Cotransporter KCC2 Polymorphism.Journal of autism and developmental disorders · 2022Article
- Comparative Assessment of TSPO Modulators on Electroencephalogram Activity and Exploratory Behavior.Frontiers in pharmacology · 2022Article
- Plasticity impairment alters community structure but permits successful pattern separation in a hippocampal network model.Frontiers in cellular neuroscience · 2022Article
- Short- and Long-Range Connections Differentially Modulate the Dynamics and State of Small-World Networks.Frontiers in computational neuroscience · 2021Article
- Neuronal Degeneration Impairs Rhythms Between Connected Microcircuits.Frontiers in computational neuroscience · 2020Article
- Frequency-Dependent Changes in Resting State Electroencephalogram Functional Networks after Traumatic Brain Injury in Piglets.Journal of neurotrauma · 2019Article
- Altered Neural Networks in the Papez Circuit: Implications for Cognitive Dysfunction after Cerebral Ischemia.Journal of Alzheimer's disease : JAD · 2019Review
- Deep brain stimulation for the treatment of disorders of consciousness and cognition in traumatic brain injury patients: a review.Neurosurgical focus · 2018Review
- Oscillatory Activity in the Cortex, Motor Thalamus and Nucleus Reticularis Thalami in Acute TTX and Chronic 6-OHDA Dopamine-Depleted Animals.Frontiers in neurology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Traumatic brain injury (TBI) can result in persistent cognitive, behavioral and emotional deficits. However, the vast majority of patients are not chronically hospitalized; rather they have to manage their disabilities once they are discharged to home. Promoting recovery to pre-injury level is important from a patient care as well as a societal perspective. Electrical neuromodulation is one approach that has shown promise in alleviating symptoms associated with neurological disorders such as in Parkinson's disease (PD) and epilepsy. Consistent with this perspective, both animal and clinical studies have revealed that TBI alters physiological oscillatory rhythms. More recently several studies demonstrated that low frequency stimulation improves cognitive outcome in models of TBI. Specifically, stimulation of the septohippocampal circuit in the theta frequency entrained oscillations and improved spatial learning following TBI. In order to evaluate the potential of electrical deep brain stimulation for clinical translation we review the basic neurophysiology of oscillations, their role in cognition and how they are changed post-TBI. Furthermore, we highlight several factors for future pre-clinical and clinical studies to consider, with the hope that it will promote a hypothesis driven approach to subsequent experimental designs and ultimately successful translation to improve outcome in patients with TBI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.