ReviewEXCLI journal2013
High therapeutic potential of Spilanthes acmella: A review.
Review in EXCLI journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed.
- Development of an Efficient In Vitro Propagation Method forMethods and protocols · 2026Article
- Article
- Anti-hyperplastic effects of Acmella oleracea flower and leaf extracts in prostate cell lines and in spontaneously hypertensive rats.Journal of molecular histology · 2026Article
- GC-MS-Identified Alkamides and Evaluation of the Anti-Inflammatory, Antibacterial, and Antioxidant Activities of WildInternational journal of molecular sciences · 2025Article
- The Multitarget Antinociceptive Compound Affinin and Its Effects on Hypothermia, Hypolocomotion, and Sickness Behavior in Lipopolysaccharide-Treated Mice.Molecules (Basel, Switzerland) · 2025Article
- Effects of thePlants (Basel, Switzerland) · 2025Article
- Short-term effects of oral dissolving film on halitosis and oral pathogenic bacteria: a pilot non-randomized controlled trial.Frontiers in microbiology · 2025Article
- Effect of Herbal Extract ofInternational journal of clinical pediatric dentistry · 2024Article
- Preliminary Studies about Valorization ofInternational journal of molecular sciences · 2024Article
- Use of Buzz Buttons to Illustrate Taste Perception Principles in a Sensation and Perception Laboratory Exercise.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2024Article
- Article
- A Review of the Chemistry and Biological Activities ofPlants (Basel, Switzerland) · 2022Review
- Sesquiterpenoid lactones as potential anti-cancer agents: an update on molecular mechanisms and recent studies.Cancer cell international · 2022Review
- Article
- Potential Antioxidant and Anti-Inflammatory Effects ofInternational journal of environmental research and public health · 2021Review
- An Efficient Method for the Genetic Transformation ofPlants (Basel, Switzerland) · 2021Article
- Mechanisms and Neuroprotective Activities of Stigmasterol Against Oxidative Stress-Induced Neuronal Cell DeathFrontiers in nutrition · 2021Article
- Discovery of Spilanthol Endoperoxide as a Redox Natural Compound Active against Mammalian Prx3 andAntioxidants (Basel, Switzerland) · 2020Article
- Chemical composition and broad-spectrum anthelmintic activity of a cultivar of toothache plant,Pharmaceutical biology · 2020Article
- Butein, isoliquiritigenin, and scopoletin attenuate neurodegenerationRSC advances · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spilanthes acmella, a well known antitoothache plant with high medicinal usages, has been recognized as an important medicinal plant and has an increasingly high demand worldwide. From its traditional uses in health care and food, extensive phytochemical studies have been reported. This review provides an overview and general description of the plant species, bioactive metabolites and important pharmacological activities including the preparation, purification and in vitro large-scale production. Structure-activity relationships of the bioactive compounds have been discussed. Considering data from the literature, it could be demonstrated that S. acmella possesses diverse bioactive properties and immense utilization in medicine, health care, cosmetics and as health supplements. As a health food, it is enriched with high therapeutic value with high potential for further development.
Indexed as
Identifiers
27092032PMC4827075What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.