ArticleSleep2016
Sleep Apnea and Obstructive Airway Disease in Older Men: Outcomes of Sleep Disorders in Older Men Study.
Article in Sleep, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The trial behind it
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Who cites it
17 citing papers in PubMed, 37 citations in OpenAlex.
- Real-world generalizability of sleep apnea-related polysomnographic metrics and their associations with clinical comorbidities.Annals of the American Thoracic Society · 2026Article
- Sleep Health and Associations With Early Cardiovascular Risk in U.S. Collegiate Female Athletes.JACC. Advances · 2025Article
- Sleep Deficiency in Obstructive Sleep Apnea.Sleep medicine clinics · 2024Review
- Unraveling the causality between chronic obstructive pulmonary disease and its common comorbidities using bidirectional Mendelian randomization.European journal of medical research · 2024Article
- Fabric computing: Concepts, opportunities, and challenges.Innovation (Cambridge (Mass.)) · 2022Review
- Impact of Positive Airway Pressure Therapy Adherence on Outcomes in Patients with Obstructive Sleep Apnea and Chronic Obstructive Pulmonary Disease.American journal of respiratory and critical care medicine · 2022Observational
- Bidirectional relationships of comorbidity with obstructive sleep apnoea.European respiratory review : an official journal of the European Respiratory Society · 2022Review
- Sleep Deficiency in Obstructive Sleep Apnea.Clinics in chest medicine · 2022Review
- Association between comorbid sleep apnoea-hypopnoea syndrome and prognosis of intensive care patients: a retrospective cohort study.BMJ open · 2021Article
- Polysomnography findings of patients with overlap syndrome according to severity of lower airway obstruction.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021Article
- Prospective Study of Nocturnal Desaturation in Patients Receiving Home Oxygen Therapy.Internal medicine (Tokyo, Japan) · 2021Article
- Moderate-to-Severe Obstructive Sleep Apnea and Cognitive Function Impairment in Patients with COPD.International journal of chronic obstructive pulmonary disease · 2020Article
- Polysomnographic features of low arousal threshold in overlap syndrome involving obstructive sleep apnea and chronic obstructive pulmonary disease.Sleep & breathing = Schlaf & Atmung · 2019Article
- Article
- Sleep in chronic respiratory disease: COPD and hypoventilation disorders.European respiratory review : an official journal of the European Respiratory Society · 2019Review
- Comorbid obstructive sleep apnoea and chronic obstructive pulmonary disease and the risk of cardiovascular disease.Journal of thoracic disease · 2018Review
- Predictors of Sleep Apnea in the Canadian Population.Canadian respiratory journal · 2018Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
STUDY
objectivesTo evaluate the association between obstructive airway disease (OAD) and sleep apnea in older men.
methodsA community-based cross-sectional study of 853 community-dwelling older men (mean age 80.7 ± 4.1 years [range 73 to 90]) across 6 centers in the United States from the Outcomes of Sleep Disorders in Older Men Study. Sleep was objectively measured using full in-home polysomnography and lung function was objectively measured using spirometry. The association of OAD (pre-bronchodilator FEV1/FVC ratio < 0.7 and FEV1 < 80% predicted) and sleep apnea (apnea-hypopnea index [AHI] ≥ 15 events/hour) was assessed using logistic regression.
resultsOAD and sleep apnea were identified in 111 (13.0%) and 247 (29.0%) men, respectively. In univariate analysis, participants with OAD had a lower AHI (mean ± SD; 8.7 ± 11.7 vs. 12.7 ± 13.8, P = 0.0009) and a lower prevalence of sleep apnea (14.4 vs. 31.1%, P = 0.0003) compared to participants without OAD. OAD remained independently associated with a lower odds of sleep apnea (odds ratio 0.30, 95% CI 0.16 to 0.55, P = 0.0001) after adjustment for demographics, body composition, smoking, and potential mediators (arousal index, time spent in rapid eye movement sleep). Individuals with OAD and sleep apnea (n = 16) had an increased arousal index and lower oxygen saturation level as compared to individuals with OAD alone (P values < 0.05).
conclusionsObstructive airway disease was associated with a lower prevalence of sleep apnea in a cohort of community-dwelling elderly men, and unexplained by differences in adiposity or sleep architecture. Although uncommon in this cohort, coexisting sleep apnea and OAD was associated with increased sleep fragmentation and nocturnal oxygen desaturation compared to OAD alone.
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