Evidence map›Paper›PMID 27091491›Full record

ArticleTrends in endocrinology and metabolism: TEM2016

Non-Genetic Transmission of Obesity - It's in Your Epigenes.

Elena Loche, Susan E Ozanne

Abstract readComment
PubMed Publisher
In one paragraph

Article in Trends in endocrinology and metabolism: TEM, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Development of an mHealth Platform for Adolescent Obesity Prevention: User-Centered Design Approach.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Elena LocheUniversity of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.
Susan E OzanneUniversity of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK. Electronic address: seo10@cam.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BB/M001636/1British Heart Foundation FS/09/029/27902British Heart Foundation PG/14/20/30769Medical Research Council MC_UU_12012/4
6 · The paper itself

Abstract

Obesity and its related metabolic comorbidities can be inherited across generations through non-genetic mechanisms. In a recent report, Huypens et al., using an in vitro fertilization approach, provide evidence that exposure to a high-fat diet modifies egg and sperm epigenetic information, rendering the progeny more prone to obesity.

Indexed as

Diet, High-FatEpigenesis, GeneticFemaleHumansMaleMaternal ExposureObesityPaternal Exposure

Identifiers

PMID27091491

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.