ArticleBMC infectious diseases2016
Clinically mild encephalitis/encephalopathy with a reversible splenial lesion caused by methicillin-sensitive Staphylococcus aureus bacteremia with toxic shock syndrome: a case report.
Article in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS).PCN reports : psychiatry and clinical neurosciences · 2024Article
- Phenome-wide association study identifies new clinical phenotypes associated with Staphylococcus aureus infections.PloS one · 2024Article
- Clinical and imaging features of reversible splenial lesion syndrome with language disorder.Translational neuroscience · 2020Article
- Review
- MERS associated with bacterial translocation in a pediatric patient with congenital portal vein hypoplasia: A case report.Experimental and therapeutic medicine · 2018Article
- Article
- Encephalitis with reversible splenial and deep cerebral white matter lesions associated with Epstein-Barr virus infection in adults.Neuropsychiatric disease and treatment · 2017Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundClinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a mild encephalopathy caused by various pathological processes, but encephalopathy due to bacteria is rare. CASE PRESENTATION: We report the case of a 45-year-old Japanese woman who on receiving chemotherapy for advanced breast cancer developed an altered mental status and dysarthria soon after fever from infection of a subcutaneous implantable port. Staphylococcus aureus was detected in her blood cultures. Magnetic resonance imaging (MRI) revealed an ovoid lesion in the central portion of the splenium of the corpus callosum (SCC). Although hypotension was not observed, we diagnosed probable toxic shock syndrome (TSS) based on fever (temperature: >38.9 °C), altered mental status, erythema, desquamation, thrombocytopenia, liver dysfunction, and creatine phosphokinase elevation. We administered antimicrobial therapy and her neurological symptoms improved gradually. The lesion in the SCC completely disappeared on MRI 7 days after disease onset.
conclusionsWe diagnosed this case as MERS caused by S. aureus bacteremia with TSS. This is the first report of such a case, and we suggest that when a TSS patient presents with neurological symptoms, the possibility of MERS should be considered.
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