ReviewCritical care (London, England)2016
Strategies to optimize respiratory muscle function in ICU patients.
Review in Critical care (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Low-Medium and High-Intensity Inspiratory Muscle Training in Critically Ill Patients: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Effects of levosimendan on respiratory muscle function in patients weaning from mechanical ventilation.Intensive care medicine · 2019Trial
- Abdominal functional electrical stimulation to assist ventilator weaning in critical illness: a double-blinded, randomised, sham-controlled pilot study.Critical care (London, England) · 2019Trial
- Persistent inspiratory muscle weakness among extubated patients after prolonged intubation is frequent and can be predicted early by maximal inspiratory pressure measured 12 days after its initial diagnosis: a prospective observational study.Critical care (London, England) · 2025Observational
- Intensive care unit-acquired muscle atrophy and weakness in critical illness: a review of long-term recovery strategies.Acute and critical care · 2025Article
- Disease entity impacts muscle wasting in the ICU with COVID-19 patients losing muscle nearly twice as fast.Scientific reports · 2025Article
- Respiratory Muscle Dysfunction and Associated Risk Factors Following COVID-19-Related Hospitalisation.Life (Basel, Switzerland) · 2025Article
- Normative Values and Calculation Formulas of Respiratory Muscle Strength of Adults in Turkish Society: A Population-based Study.Thoracic research and practice · 2024Article
- Phrenic nerve stimulation in an ovine model with temporary removable pacing leads.Journal of thoracic disease · 2022Article
- Nocebo Effects of Clinical Communication and Placebo Effects of Positive Suggestions on Respiratory Muscle Strength.Frontiers in psychology · 2022Article
- High-Intensity Inspiratory Muscle Training Improves Scalene and Sternocleidomastoid Muscle Oxygenation Parameters in Patients With Weaning Difficulties: A Randomized Controlled Trial.Frontiers in physiology · 2022Article
- Respiratory Muscle Rehabilitation in Patients with Prolonged Mechanical Ventilation: A Targeted Approach.Critical care (London, England) · 2020Review
- Expiratory muscle dysfunction in critically ill patients: towards improved understanding.Intensive care medicine · 2019Review
- Ventilator-induced diaphragm dysfunction: translational mechanisms lead to therapeutical alternatives in the critically ill.Intensive care medicine experimental · 2019Review
- Safety and efficacy of volume-based feeding in critically ill, mechanically ventilated adults using the 'Protein & Energy Requirements Fed for Every Critically ill patient every Time' (PERFECT) protocol: a before-and-after study.Critical care (London, England) · 2019Article
- European Respiratory Society International Congress 2018: highlights from Assembly 2 on respiratory intensive care.ERJ open research · 2019Review
- Ventilator-induced diaphragm dysfunction in critical illness.Experimental biology and medicine (Maywood, N.J.) · 2018Review
- Article
- Critical illness-associated diaphragm weakness.Intensive care medicine · 2017Review
- Novel insights in ICU-acquired respiratory muscle dysfunction: implications for clinical care.Critical care (London, England) · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Respiratory muscle dysfunction may develop rapidly in critically ill ventilated patients and is associated with increased morbidity, length of intensive care unit stay, costs, and mortality. This review briefly discusses the pathophysiology of respiratory muscle dysfunction in intensive care unit patients and then focuses on strategies that prevent the development of muscle weakness or, if weakness has developed, how respiratory muscle function may be improved. We propose a simple strategy for how these can be implemented in clinical care.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.